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Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.
Taschler U, Radner FP, Heier C, Schreiber R, Schweiger M, Schoiswohl G, Preiss-Landl K, Jaeger D, Reiter B, Koefeler HC, Wojciechowski J, Theussl C, Penninger JM, Lass A, Haemmerle G, Zechner R, Zimmermann R. Taschler U, et al. J Biol Chem. 2011 May 20;286(20):17467-77. doi: 10.1074/jbc.M110.215434. Epub 2011 Mar 23. J Biol Chem. 2011. PMID: 21454566 Free PMC article.
Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Pajed L, Taschler U, Tilp A, Hofer P, Kotzbeck P, Kolleritsch S, Radner FPW, Pototschnig I, Wagner C, Schratter M, Eder S, Huetter S, Schreiber R, Haemmerle G, Eichmann TO, Schweiger M, Hoefler G, Kershaw EE, Lass A, Schoiswohl G. Pajed L, et al. Among authors: taschler u. Commun Biol. 2021 Mar 10;4(1):323. doi: 10.1038/s42003-021-01858-z. Commun Biol. 2021. PMID: 33692445 Free PMC article.
The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes.
Rengachari S, Bezerra GA, Riegler-Berket L, Gruber CC, Sturm C, Taschler U, Boeszoermenyi A, Dreveny I, Zimmermann R, Gruber K, Oberer M. Rengachari S, et al. Among authors: taschler u. Biochim Biophys Acta. 2012 Jul;1821(7):1012-21. doi: 10.1016/j.bbalip.2012.04.006. Epub 2012 Apr 27. Biochim Biophys Acta. 2012. PMID: 22561231 Free PMC article.
The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome.
Thomas G, Betters JL, Lord CC, Brown AL, Marshall S, Ferguson D, Sawyer J, Davis MA, Melchior JT, Blume LC, Howlett AC, Ivanova PT, Milne SB, Myers DS, Mrak I, Leber V, Heier C, Taschler U, Blankman JL, Cravatt BF, Lee RG, Crooke RM, Graham MJ, Zimmermann R, Brown HA, Brown JM. Thomas G, et al. Among authors: taschler u. Cell Rep. 2013 Oct 31;5(2):508-20. doi: 10.1016/j.celrep.2013.08.047. Epub 2013 Oct 3. Cell Rep. 2013. PMID: 24095738 Free PMC article.
Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity.
Schreiber R, Hofer P, Taschler U, Voshol PJ, Rechberger GN, Kotzbeck P, Jaeger D, Preiss-Landl K, Lord CC, Brown JM, Haemmerle G, Zimmermann R, Vidal-Puig A, Zechner R. Schreiber R, et al. Among authors: taschler u. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13850-5. doi: 10.1073/pnas.1516004112. Epub 2015 Oct 27. Proc Natl Acad Sci U S A. 2015. PMID: 26508640 Free PMC article.
43 results