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Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo.
Albert K, Raymundo DP, Panhelainen A, Eesmaa A, Shvachiy L, Araújo GR, Chmielarz P, Yan X, Singh A, Cordeiro Y, Palhano FL, Foguel D, Luk KC, Domanskyi A, Voutilainen MH, Huttunen HJ, Outeiro TF, Saarma M, Almeida MS, Airavaara M. Albert K, et al. Among authors: panhelainen a. Mol Ther. 2021 Sep 1;29(9):2821-2840. doi: 10.1016/j.ymthe.2021.04.035. Epub 2021 May 1. Mol Ther. 2021. PMID: 33940158 Free PMC article.
Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice.
Lindahl M, Chalazonitis A, Palm E, Pakarinen E, Danilova T, Pham TD, Setlik W, Rao M, Võikar V, Huotari J, Kopra J, Andressoo JO, Piepponen PT, Airavaara M, Panhelainen A, Gershon MD, Saarma M. Lindahl M, et al. Among authors: panhelainen a. Neurobiol Dis. 2020 Feb;134:104696. doi: 10.1016/j.nbd.2019.104696. Epub 2019 Nov 26. Neurobiol Dis. 2020. PMID: 31783118 Free PMC article.
GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function.
Kumar A, Kopra J, Varendi K, Porokuokka LL, Panhelainen A, Kuure S, Marshall P, Karalija N, Härma MA, Vilenius C, Lilleväli K, Tekko T, Mijatovic J, Pulkkinen N, Jakobson M, Jakobson M, Ola R, Palm E, Lindahl M, Strömberg I, Võikar V, Piepponen TP, Saarma M, Andressoo JO. Kumar A, et al. Among authors: panhelainen a. PLoS Genet. 2015 Dec 17;11(12):e1005710. doi: 10.1371/journal.pgen.1005710. eCollection 2015 Dec. PLoS Genet. 2015. PMID: 26681446 Free PMC article.
Conditioned Aversion and Neuroplasticity Induced by a Superagonist of Extrasynaptic GABAA Receptors: Correlation With Activation of the Oval BNST Neurons and CRF Mechanisms.
de Miguel E, Vekovischeva O, Elsilä LV, Panhelainen A, Kankuri E, Aitta-Aho T, Korpi ER. de Miguel E, et al. Among authors: panhelainen a. Front Mol Neurosci. 2019 May 24;12:130. doi: 10.3389/fnmol.2019.00130. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31178693 Free PMC article.
20 results