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542 results

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Page 1
Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice.
Shing DC, Trubia M, Marchesi F, Radaelli E, Belloni E, Tapinassi C, Scanziani E, Mecucci C, Crescenzi B, Lahortiga I, Odero MD, Zardo G, Gruszka A, Minucci S, Di Fiore PP, Pelicci PG. Shing DC, et al. Among authors: pelicci pg. J Clin Invest. 2007 Dec;117(12):3696-707. doi: 10.1172/JCI32390. J Clin Invest. 2007. PMID: 18037989 Free PMC article.
A monoclonal antibody against mutated nucleophosmin 1 for the molecular diagnosis of acute myeloid leukemias.
Gruszka AM, Lavorgna S, Consalvo MI, Ottone T, Martinelli C, Cinquanta M, Ossolengo G, Pruneri G, Buccisano F, Divona M, Cedrone M, Ammatuna E, Venditti A, de Marco A, Lo-Coco F, Pelicci PG. Gruszka AM, et al. Among authors: pelicci pg. Blood. 2010 Sep 23;116(12):2096-102. doi: 10.1182/blood-2010-01-266908. Epub 2010 Jun 10. Blood. 2010. PMID: 20538791 Free article.
The self-association coiled-coil domain of PML is sufficient for the oncogenic conversion of the retinoic acid receptor (RAR) alpha.
Occhionorelli M, Santoro F, Pallavicini I, Gruszka A, Moretti S, Bossi D, Viale A, Shing D, Ronzoni S, Muradore I, Soncini M, Pruneri G, Rafaniello P, Viale G, Pelicci PG, Minucci S. Occhionorelli M, et al. Among authors: pelicci pg. Leukemia. 2011 May;25(5):814-20. doi: 10.1038/leu.2011.18. Epub 2011 Feb 18. Leukemia. 2011. PMID: 21331069
Is PML a Tumor Suppressor?
Mazza M, Pelicci PG. Mazza M, et al. Among authors: pelicci pg. Front Oncol. 2013 Jul 9;3:174. doi: 10.3389/fonc.2013.00174. eCollection 2013. Front Oncol. 2013. PMID: 23847764 Free PMC article.
PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.
Ronchini C, Brozzi A, Riva L, Luzi L, Gruszka AM, Melloni GEM, Scanziani E, Dharmalingam G, Mutarelli M, Belcastro V, Lavorgna S, Rossi V, Spinelli O, Biondi A, Rambaldi A, Lo-Coco F, di Bernardo D, Pelicci PG. Ronchini C, et al. Among authors: pelicci pg. Leukemia. 2017 Sep;31(9):1975-1986. doi: 10.1038/leu.2016.386. Epub 2016 Dec 27. Leukemia. 2017. PMID: 28025581
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Dellino GI, Palluzzi F, Chiariello AM, Piccioni R, Bianco S, Furia L, De Conti G, Bouwman BAM, Melloni G, Guido D, Giacò L, Luzi L, Cittaro D, Faretta M, Nicodemi M, Crosetto N, Pelicci PG. Dellino GI, et al. Among authors: pelicci pg. Nat Genet. 2019 Jun;51(6):1011-1023. doi: 10.1038/s41588-019-0421-z. Epub 2019 May 20. Nat Genet. 2019. PMID: 31110352
High-Fat Diet Promotes Acute Promyelocytic Leukemia through PPARδ-Enhanced Self-renewal of Preleukemic Progenitors.
Mazzarella L, Falvo P, Adinolfi M, Tini G, Gatti E, Piccioni R, Bonetti E, Gavilán E, Valli D, Gruszka A, Bodini M, Gallo B, Orecchioni S, de Michele G, Migliaccio E, Duso BA, Roerink S, Stratton M, Bertolini F, Alcalay M, Dellino GI, Pelicci PG. Mazzarella L, et al. Among authors: pelicci pg. Cancer Prev Res (Phila). 2024 Feb 2;17(2):59-75. doi: 10.1158/1940-6207.CAPR-23-0246. Cancer Prev Res (Phila). 2024. PMID: 37956420
542 results