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High-throughput genotyping assays for identification of glycophorin B deletion variants in population studies.
Amuzu DS, Rockett KA, Leffler EM, Ansah F, Amoako N, Morang'a CM, Hubbart C, Rowlands K, Jeffreys AE, Amenga-Etego LN, Kwiatkowski DP, Awandare GA. Amuzu DS, et al. Among authors: hubbart c. Exp Biol Med (Maywood). 2021 Apr;246(8):916-928. doi: 10.1177/1535370220968545. Epub 2020 Dec 16. Exp Biol Med (Maywood). 2021. PMID: 33325748 Free PMC article. Clinical Trial.
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing.
Manske M, Miotto O, Campino S, Auburn S, Almagro-Garcia J, Maslen G, O'Brien J, Djimde A, Doumbo O, Zongo I, Ouedraogo JB, Michon P, Mueller I, Siba P, Nzila A, Borrmann S, Kiara SM, Marsh K, Jiang H, Su XZ, Amaratunga C, Fairhurst R, Socheat D, Nosten F, Imwong M, White NJ, Sanders M, Anastasi E, Alcock D, Drury E, Oyola S, Quail MA, Turner DJ, Ruano-Rubio V, Jyothi D, Amenga-Etego L, Hubbart C, Jeffreys A, Rowlands K, Sutherland C, Roper C, Mangano V, Modiano D, Tan JC, Ferdig MT, Amambua-Ngwa A, Conway DJ, Takala-Harrison S, Plowe CV, Rayner JC, Rockett KA, Clark TG, Newbold CI, Berriman M, MacInnis B, Kwiatkowski DP. Manske M, et al. Among authors: hubbart c. Nature. 2012 Jul 19;487(7407):375-9. doi: 10.1038/nature11174. Nature. 2012. PMID: 22722859 Free PMC article.
Resistance to malaria through structural variation of red blood cell invasion receptors.
Leffler EM, Band G, Busby GBJ, Kivinen K, Le QS, Clarke GM, Bojang KA, Conway DJ, Jallow M, Sisay-Joof F, Bougouma EC, Mangano VD, Modiano D, Sirima SB, Achidi E, Apinjoh TO, Marsh K, Ndila CM, Peshu N, Williams TN, Drakeley C, Manjurano A, Reyburn H, Riley E, Kachala D, Molyneux M, Nyirongo V, Taylor T, Thornton N, Tilley L, Grimsley S, Drury E, Stalker J, Cornelius V, Hubbart C, Jeffreys AE, Rowlands K, Rockett KA, Spencer CCA, Kwiatkowski DP; Malaria Genomic Epidemiology Network. Leffler EM, et al. Among authors: hubbart c. Science. 2017 Jun 16;356(6343):eaam6393. doi: 10.1126/science.aam6393. Epub 2017 May 18. Science. 2017. PMID: 28522690 Free PMC article.
Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ‑α 3.7I form of α-thalassaemia using genome-wide microarray data.
Ndila CM, Nyirongo V, Macharia AW, Jeffreys AE, Rowlands K, Hubbart C, Busby GBJ, Band G, Harding RM, Rockett KA, Williams TN; MalariaGEN Consortium. Ndila CM, et al. Among authors: hubbart c. Wellcome Open Res. 2021 Sep 22;5:287. doi: 10.12688/wellcomeopenres.16320.2. eCollection 2020. Wellcome Open Res. 2021. PMID: 34632085 Free PMC article.
Malaria protection due to sickle haemoglobin depends on parasite genotype.
Band G, Leffler EM, Jallow M, Sisay-Joof F, Ndila CM, Macharia AW, Hubbart C, Jeffreys AE, Rowlands K, Nguyen T, Gonçalves S, Ariani CV, Stalker J, Pearson RD, Amato R, Drury E, Sirugo G, d'Alessandro U, Bojang KA, Marsh K, Peshu N, Saelens JW, Diakité M, Taylor SM, Conway DJ, Williams TN, Rockett KA, Kwiatkowski DP. Band G, et al. Among authors: hubbart c. Nature. 2022 Feb;602(7895):106-111. doi: 10.1038/s41586-021-04288-3. Epub 2021 Dec 9. Nature. 2022. PMID: 34883497 Free PMC article.
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study.
Ndila CM, Uyoga S, Macharia AW, Nyutu G, Peshu N, Ojal J, Shebe M, Awuondo KO, Mturi N, Tsofa B, Sepúlveda N, Clark TG, Band G, Clarke G, Rowlands K, Hubbart C, Jeffreys A, Kariuki S, Marsh K, Mackinnon M, Maitland K, Kwiatkowski DP, Rockett KA, Williams TN; MalariaGEN Consortium. Ndila CM, et al. Among authors: hubbart c. Lancet Haematol. 2018 Aug;5(8):e333-e345. doi: 10.1016/S2352-3026(18)30107-8. Epub 2018 Jul 20. Lancet Haematol. 2018. PMID: 30033078 Free PMC article.
A high throughput multi-locus insecticide resistance marker panel for tracking resistance emergence and spread in Anopheles gambiae.
Lucas ER, Rockett KA, Lynd A, Essandoh J, Grisales N, Kemei B, Njoroge H, Hubbart C, Rippon EJ, Morgan J, Van't Hof AE, Ochomo EO, Kwiatkowski DP, Weetman D, Donnelly MJ. Lucas ER, et al. Among authors: hubbart c. Sci Rep. 2019 Sep 16;9(1):13335. doi: 10.1038/s41598-019-49892-6. Sci Rep. 2019. PMID: 31527637 Free PMC article.
Imputation-based meta-analysis of severe malaria in three African populations.
Band G, Le QS, Jostins L, Pirinen M, Kivinen K, Jallow M, Sisay-Joof F, Bojang K, Pinder M, Sirugo G, Conway DJ, Nyirongo V, Kachala D, Molyneux M, Taylor T, Ndila C, Peshu N, Marsh K, Williams TN, Alcock D, Andrews R, Edkins S, Gray E, Hubbart C, Jeffreys A, Rowlands K, Schuldt K, Clark TG, Small KS, Teo YY, Kwiatkowski DP, Rockett KA, Barrett JC, Spencer CC; Malaria Genomic Epidemiology Network. Band G, et al. Among authors: hubbart c. PLoS Genet. 2013 May;9(5):e1003509. doi: 10.1371/journal.pgen.1003509. Epub 2013 May 23. PLoS Genet. 2013. PMID: 23717212 Free PMC article.
44 results