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Discovery of 7-aminophenanthridin-6-one as a new scaffold for matrix metalloproteinase inhibitors with multitarget neuroprotective activity.
Rocchi D, Blázquez-Barbadillo C, Agamennone M, Laghezza A, Tortorella P, Vicente-Zurdo D, Rosales-Conrado N, Moyano P, Pino JD, González JF, Menéndez JC. Rocchi D, et al. Among authors: pino jd. Eur J Med Chem. 2021 Jan 15;210:113061. doi: 10.1016/j.ejmech.2020.113061. Epub 2020 Nov 30. Eur J Med Chem. 2021. PMID: 33310289
Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment.
Moyano P, García JM, García J, Anadon MJ, Naval MV, Frejo MT, Sola E, Pelayo A, Pino JD. Moyano P, et al. Among authors: pino jd. Ecotoxicol Environ Saf. 2020 Oct 15;203:110975. doi: 10.1016/j.ecoenv.2020.110975. Epub 2020 Jul 14. Ecotoxicol Environ Saf. 2020. PMID: 32678756
Single and repeated bisphenol A treatment induces ROS, Aβ and hyperphosphorylated-tau accumulation, and insulin pathways disruption, through HDAC2 and PTP1B overexpression, leading to SN56 cholinergic apoptotic cell death.
Flores A, Moyano P, Sola E, García JM, García J, Anadon MJ, Frejo MT, Naval MV, Fernadez MC, Pino JD. Flores A, et al. Among authors: pino jd. Food Chem Toxicol. 2022 Dec;170:113500. doi: 10.1016/j.fct.2022.113500. Epub 2022 Oct 29. Food Chem Toxicol. 2022. PMID: 36374790
Use of risk chart algorithms for the identification of psoriatic arthritis patients at high risk for cardiovascular disease: findings derived from the project CARMA cohort after a 7.5-year follow-up period.
Polo Y La Borda J, Castañeda S, Heras-Recuero E, Sánchez-Alonso F, Plaza Z, García Gómez C, Ferraz-Amaro I, Sanchez-Costa JT, Sánchez-González OC, Turrión-Nieves AI, Perez-Alcalá A, Pérez-García C, González-Juanatey C, Llorca J, Gonzalez-Gay MA; CARMA Project Collaborative Group. Polo Y La Borda J, et al. RMD Open. 2024 Apr 17;10(2):e004207. doi: 10.1136/rmdopen-2024-004207. RMD Open. 2024. PMID: 38631846 Free PMC article.
17 results