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Heterozygous disruption of ALAS1 in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver.
van Wijk K, Akabane T, Kimura T, Saitoh S, Okano S, Kelly VP, Takagi M, Kodama K, Takahashi K, Tanaka T, Nakajima M, Nakajima O. van Wijk K, et al. Among authors: okano s. Arch Biochem Biophys. 2021 Jan 15;697:108721. doi: 10.1016/j.abb.2020.108721. Epub 2020 Dec 8. Arch Biochem Biophys. 2021. PMID: 33307066 Free article.
5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice.
Saitoh S, Okano S, Nohara H, Nakano H, Shirasawa N, Naito A, Yamamoto M, Kelly VP, Takahashi K, Tanaka T, Nakajima M, Nakajima O. Saitoh S, et al. Among authors: okano s. PLoS One. 2018 Jan 24;13(1):e0189593. doi: 10.1371/journal.pone.0189593. eCollection 2018. PLoS One. 2018. PMID: 29364890 Free PMC article.
In vivo oxygen imaging using green fluorescent protein.
Takahashi E, Takano T, Nomura Y, Okano S, Nakajima O, Sato M. Takahashi E, et al. Among authors: okano s. Am J Physiol Cell Physiol. 2006 Oct;291(4):C781-7. doi: 10.1152/ajpcell.00067.2006. Epub 2006 May 31. Am J Physiol Cell Physiol. 2006. PMID: 16738007 Free article.
533 results