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224 results

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Page 1
Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Schiffner T, Phung I, Ray R, Irimia A, Tian M, Swanson O, Lee JH, Lee CD, Marina-Zárate E, Cho SY, Huang J, Ozorowski G, Skog PD, Serra AM, Rantalainen K, Allen JD, Baboo S, Rodriguez OL, Himansu S, Zhou J, Hurtado J, Flynn CT, McKenney K, Havenar-Daughton C, Saha S, Shields K, Schulze S, Smith ML, Liang CH, Toy L, Pecetta S, Lin YC, Willis JR, Sesterhenn F, Kulp DW, Hu X, Cottrell CA, Zhou X, Ruiz J, Wang X, Nair U, Kirsch KH, Cheng HL, Davis J, Kalyuzhniy O, Liguori A, Diedrich JK, Ngo JT, Lewis V, Phelps N, Tingle RD, Spencer S, Georgeson E, Adachi Y, Kubitz M, Eskandarzadeh S, Elsliger MA, Amara RR, Landais E, Briney B, Burton DR, Carnathan DG, Silvestri G, Watson CT, Yates JR 3rd, Paulson JC, Crispin M, Grigoryan G, Ward AB, Sok D, Alt FW, Wilson IA, Batista FD, Crotty S, Schief WR. Schiffner T, et al. Among authors: cottrell ca. Nat Immunol. 2024 May 30. doi: 10.1038/s41590-024-01833-w. Online ahead of print. Nat Immunol. 2024. PMID: 38816615
mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models.
Wang X, Cottrell CA, Hu X, Ray R, Bottermann M, Villavicencio PM, Yan Y, Xie Z, Warner JE, Ellis-Pugh JR, Kalyuzhniy O, Liguori A, Willis JR, Menis S, Rämisch S, Eskandarzadeh S, Kubitz M, Tingle R, Phelps N, Groschel B, Himansu S, Carfi A, Kirsch KH, Weldon SR, Nair U, Schief WR, Batista FD. Wang X, et al. Among authors: cottrell ca. Sci Immunol. 2024 May 10;9(95):eadn0622. doi: 10.1126/sciimmunol.adn0622. Epub 2024 May 16. Sci Immunol. 2024. PMID: 38753808
Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice.
Cottrell CA, Hu X, Lee JH, Skog P, Luo S, Flynn CT, McKenney KR, Hurtado J, Kalyuzhniy O, Liguori A, Willis JR, Landais E, Raemisch S, Chen X, Baboo S, Himansu S, Diedrich JK, Duan H, Cheng C, Schiffner T, Bader DLV, Kulp DW, Tingle R, Georgeson E, Eskandarzadeh S, Alavi N, Lu D, Sincomb T, Kubitz M, Mullen TM, Yates JR 3rd, Paulson JC, Mascola JR, Alt FW, Briney B, Sok D, Schief WR. Cottrell CA, et al. Sci Transl Med. 2024 May 22;16(748):eadn0223. doi: 10.1126/scitranslmed.adn0223. Epub 2024 May 22. Sci Transl Med. 2024. PMID: 38753806
Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.
Steichen JM, Phung I, Salcedo E, Ozorowski G, Willis JR, Baboo S, Liguori A, Cottrell CA, Torres JL, Madden PJ, Ma KM, Sutton HJ, Lee JH, Kalyuzhniy O, Allen JD, Rodriguez OL, Adachi Y, Mullen TM, Georgeson E, Kubitz M, Burns A, Barman S, Mopuri R, Metz A, Altheide TK, Diedrich JK, Saha S, Shields K, Schultze SE, Smith ML, Schiffner T, Burton DR, Watson CT, Bosinger SE, Crispin M, Yates JR 3rd, Paulson JC, Ward AB, Sok D, Crotty S, Schief WR. Steichen JM, et al. Among authors: cottrell ca. Science. 2024 May 17;384(6697):eadj8321. doi: 10.1126/science.adj8321. Epub 2024 May 17. Science. 2024. PMID: 38753769
Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming.
deCamp AC, Corcoran MM, Fulp WJ, Willis JR, Cottrell CA, Bader DLV, Kalyuzhniy O, Leggat DJ, Cohen KW, Hyrien O, Menis S, Finak G, Ballweber-Fleming L, Srikanth A, Plyler JR, Rahaman F, Lombardo A, Philiponis V, Whaley RE, Seese A, Brand J, Ruppel AM, Hoyland W, Mahoney CR, Cagigi A, Taylor A, Brown DM, Ambrozak DR, Sincomb T, Mullen TM, Maenza J, Kolokythas O, Khati N, Bethony J, Roederer M, Diemert D, Koup RA, Laufer DS, McElrath JM, McDermott AB, Karlsson Hedestam GB, Schief WR. deCamp AC, et al. Among authors: cottrell ca. NPJ Vaccines. 2024 Mar 11;9(1):58. doi: 10.1038/s41541-024-00811-5. NPJ Vaccines. 2024. PMID: 38467663 Free article.
Full-length isoform concatenation sequencing to resolve cancer transcriptome complexity.
Wijeratne S, Gonzalez MEH, Roach K, Miller KE, Schieffer KM, Fitch JR, Leonard J, White P, Kelly BJ, Cottrell CE, Mardis ER, Wilson RK, Miller AR. Wijeratne S, et al. Among authors: cottrell ce. BMC Genomics. 2024 Jan 29;25(1):122. doi: 10.1186/s12864-024-10021-x. BMC Genomics. 2024. PMID: 38287261 Free PMC article.
Clinically significant findings in a decade-long retrospective study of prenatal chromosomal microarray testing.
Olayiwola JO, Marhabaie M, Koboldt D, Matthews T, Siemon A, Mouhlas D, Porter T, Kyle G, Myers C, Mei H, Hou YC, Babcock M, Hunter J, Schieffer KM, Akkari Y, Reshmi S, Cottrell C, Mathew MT, Leung ML. Olayiwola JO, et al. Among authors: cottrell c. Mol Genet Genomic Med. 2024 Mar;12(3):e2349. doi: 10.1002/mgg3.2349. Epub 2024 Jan 23. Mol Genet Genomic Med. 2024. PMID: 38263869 Free PMC article. Review.
A LINE-1 mediated deletion resulting in germline retinoblastoma predisposition.
Macke EL, Miller AR, Stonerock E, Olshefski R, Zajo K, Bedrosian TA, Mardis ER, Akkari YMN, Cottrell CE, Schieffer KM. Macke EL, et al. Among authors: cottrell ce. Neurooncol Adv. 2023 Dec 10;6(1):vdad163. doi: 10.1093/noajnl/vdad163. eCollection 2024 Jan-Dec. Neurooncol Adv. 2023. PMID: 38213835 Free PMC article.
224 results