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Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9-tetrahydrocannabinol-exposed rats.
Di Bartolomeo M, Stark T, Maurel OM, Iannotti FA, Kuchar M, Ruda-Kucerova J, Piscitelli F, Laudani S, Pekarik V, Salomone S, Arosio B, Mechoulam R, Maccarrone M, Drago F, Wotjak CT, Di Marzo V, Vismara M, Dell'Osso B, D'Addario C, Micale V. Di Bartolomeo M, et al. Among authors: mechoulam r. Pharmacol Res. 2021 Feb;164:105357. doi: 10.1016/j.phrs.2020.105357. Epub 2020 Dec 4. Pharmacol Res. 2021. PMID: 33285233 Free article.
Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.
Stark T, Ruda-Kucerova J, Iannotti FA, D'Addario C, Di Marco R, Pekarik V, Drazanova E, Piscitelli F, Bari M, Babinska Z, Giurdanella G, Di Bartolomeo M, Salomone S, Sulcova A, Maccarrone M, Wotjak CT, Starcuk Z Jr, Drago F, Mechoulam R, Di Marzo V, Micale V. Stark T, et al. Among authors: mechoulam r. Neuropharmacology. 2019 Mar 1;146:212-221. doi: 10.1016/j.neuropharm.2018.11.035. Epub 2018 Nov 26. Neuropharmacology. 2019. PMID: 30496751
Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment.
Stark T, Di Bartolomeo M, Di Marco R, Drazanova E, Platania CBM, Iannotti FA, Ruda-Kucerova J, D'Addario C, Kratka L, Pekarik V, Piscitelli F, Babinska Z, Fedotova J, Giurdanella G, Salomone S, Sulcova A, Bucolo C, Wotjak CT, Starcuk Z Jr, Drago F, Mechoulam R, Di Marzo V, Micale V. Stark T, et al. Among authors: mechoulam r. Biochem Pharmacol. 2020 Jul;177:114004. doi: 10.1016/j.bcp.2020.114004. Epub 2020 Apr 28. Biochem Pharmacol. 2020. PMID: 32360362
Endocannabinoid signaling at the periphery: 50 years after THC.
Maccarrone M, Bab I, Bíró T, Cabral GA, Dey SK, Di Marzo V, Konje JC, Kunos G, Mechoulam R, Pacher P, Sharkey KA, Zimmer A. Maccarrone M, et al. Among authors: mechoulam r. Trends Pharmacol Sci. 2015 May;36(5):277-96. doi: 10.1016/j.tips.2015.02.008. Epub 2015 Mar 18. Trends Pharmacol Sci. 2015. PMID: 25796370 Free PMC article. Review.
HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals.
Večeřa J, Bártová E, Krejčí J, Legartová S, Komůrková D, Rudá-Kučerová J, Štark T, Dražanová E, Kašpárek T, Šulcová A, Dekker FJ, Szymanski W, Seiser C, Weitzer G, Mechoulam R, Micale V, Kozubek S. Večeřa J, et al. Among authors: mechoulam r. J Cell Physiol. 2018 Jan;233(1):530-548. doi: 10.1002/jcp.25914. Epub 2017 May 3. J Cell Physiol. 2018. PMID: 28300292 Free PMC article.
Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats.
Ayoub SM, Smoum R, Farag M, Atwal H, Collins SA, Rock EM, Limebeer CL, Piscitelli F, Iannotti FA, Lichtman AH, Leri F, Di Marzo V, Mechoulam R, Parker LA. Ayoub SM, et al. Among authors: mechoulam r. Psychopharmacology (Berl). 2020 Sep;237(9):2753-2765. doi: 10.1007/s00213-020-05570-4. Epub 2020 Jun 16. Psychopharmacology (Berl). 2020. PMID: 32556401
Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats.
Petrie GN, Wills KL, Piscitelli F, Smoum R, Limebeer CL, Rock EM, Humphrey AE, Sheppard-Perkins M, Lichtman AH, Mechoulam R, Di Marzo V, Parker LA. Petrie GN, et al. Among authors: mechoulam r. Psychopharmacology (Berl). 2019 Sep;236(9):2623-2633. doi: 10.1007/s00213-019-05237-9. Epub 2019 Apr 16. Psychopharmacology (Berl). 2019. PMID: 30993360
Protective Effects of N-Oleoylglycine in a Mouse Model of Mild Traumatic Brain Injury.
Piscitelli F, Guida F, Luongo L, Iannotti FA, Boccella S, Verde R, Lauritano A, Imperatore R, Smoum R, Cristino L, Lichtman AH, Parker LA, Mechoulam R, Maione S, Di Marzo V. Piscitelli F, et al. Among authors: mechoulam r. ACS Chem Neurosci. 2020 Apr 15;11(8):1117-1128. doi: 10.1021/acschemneuro.9b00633. Epub 2020 Apr 2. ACS Chem Neurosci. 2020. PMID: 32017529
384 results