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Enabling drug discovery and development through single-cell imaging.
Pomerantz AK, Sari-Sarraf F, Grove KJ, Pedro L, Rudewicz PJ, Fathman JW, Krucker T. Pomerantz AK, et al. Among authors: rudewicz pj. Expert Opin Drug Discov. 2019 Feb;14(2):115-125. doi: 10.1080/17460441.2019.1559147. Epub 2018 Dec 24. Expert Opin Drug Discov. 2019. PMID: 30583700 Review.
Application of Imaging Mass Spectrometry to Assess Ocular Drug Transit.
Grove KJ, Kansara V, Prentiss M, Long D, Mogi M, Kim S, Rudewicz PJ. Grove KJ, et al. Among authors: rudewicz pj. SLAS Discov. 2017 Dec;22(10):1239-1245. doi: 10.1177/2472555217724780. Epub 2017 Aug 8. SLAS Discov. 2017. PMID: 28787579 Free article.
Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases.
Nagle A, Biggart A, Be C, Srinivas H, Hein A, Caridha D, Sciotti RJ, Pybus B, Kreishman-Deitrick M, Bursulaya B, Lai YH, Gao MY, Liang F, Mathison CJN, Liu X, Yeh V, Smith J, Lerario I, Xie Y, Chianelli D, Gibney M, Berman A, Chen YL, Jiricek J, Davis LC, Liu X, Ballard J, Khare S, Eggimann FK, Luneau A, Groessl T, Shapiro M, Richmond W, Johnson K, Rudewicz PJ, Rao SPS, Thompson C, Tuntland T, Spraggon G, Glynne RJ, Supek F, Wiesmann C, Molteni V. Nagle A, et al. Among authors: rudewicz pj. J Med Chem. 2020 Oct 8;63(19):10773-10781. doi: 10.1021/acs.jmedchem.0c00499. Epub 2020 Jul 29. J Med Chem. 2020. PMID: 32667203 Free PMC article.
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.
Reck F, Bermingham A, Blais J, Capka V, Cariaga T, Casarez A, Colvin R, Dean CR, Fekete A, Gong W, Growcott E, Guo H, Jones AK, Li C, Li F, Lin X, Lindvall M, Lopez S, McKenney D, Metzger L, Moser HE, Prathapam R, Rasper D, Rudewicz P, Sethuraman V, Shen X, Shaul J, Simmons RL, Tashiro K, Tang D, Tjandra M, Turner N, Uehara T, Vitt C, Whitebread S, Yifru A, Zang X, Zhu Q. Reck F, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755. doi: 10.1016/j.bmcl.2018.01.006. Epub 2018 Jan 4. Bioorg Med Chem Lett. 2018. PMID: 29336873
34 results