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Telomere aberrations, including telomere loss, doublets, and extreme shortening, are increased in patients with infertility.
M'kacher R, Colicchio B, Marquet V, Borie C, Najar W, Hempel WM, Heidingsfelder L, Oudrhiri N, Al Jawhari M, Wilhelm-Murer N, Miguet M, Dieterlen A, Deschênes G, Tabet AC, Junker S, Grynberg M, Fenech M, Bennaceur-Griscelli A, Voisin P, Carde P, Jeandidier E, Yardin C. M'kacher R, et al. Among authors: hempel wm. Fertil Steril. 2021 Jan;115(1):164-173. doi: 10.1016/j.fertnstert.2020.07.005. Epub 2020 Dec 4. Fertil Steril. 2021. PMID: 33272625 Free article.
Transmission of Induced Chromosomal Aberrations through Successive Mitotic Divisions in Human Lymphocytes after In Vitro and In Vivo Radiation.
Kaddour A, Colicchio B, Buron D, El Maalouf E, Laplagne E, Borie C, Ricoul M, Lenain A, Hempel WM, Morat L, Al Jawhari M, Cuceu C, Heidingsfelder L, Jeandidier E, Deschênes G, Dieterlen A, El May M, Girinsky T, Bennaceur-Griscelli A, Carde P, Sabatier L, M'kacher R. Kaddour A, et al. Among authors: hempel wm. Sci Rep. 2017 Jun 12;7(1):3291. doi: 10.1038/s41598-017-03198-7. Sci Rep. 2017. PMID: 28607452 Free PMC article.
Telomere and Centromere Staining Followed by M-FISH Improves Diagnosis of Chromosomal Instability and Its Clinical Utility.
M'kacher R, Colicchio B, Borie C, Junker S, Marquet V, Heidingsfelder L, Soehnlen K, Najar W, Hempel WM, Oudrhiri N, Wilhelm-Murer N, Miguet M, Arnoux M, Ferrapie C, Kerbrat W, Plesch A, Dieterlen A, Girinsky T, Voisin P, Deschenes G, Tabet AC, Yardin C, Bennaceur-Griscelli A, Fenech M, Carde P, Jeandidier E. M'kacher R, et al. Among authors: hempel wm. Genes (Basel). 2020 Apr 27;11(5):475. doi: 10.3390/genes11050475. Genes (Basel). 2020. PMID: 32349350 Free PMC article.
Telomere shortening: a new prognostic factor for cardiovascular disease post-radiation exposure.
M'kacher R, Girinsky T, Colicchio B, Ricoul M, Dieterlen A, Jeandidier E, Heidingsfelder L, Cuceu C, Shim G, Frenzel M, Lenain A, Morat L, Bourhis J, Hempel WM, Koscielny S, Paul JF, Carde P, Sabatier L. M'kacher R, et al. Among authors: hempel wm. Radiat Prot Dosimetry. 2015 Apr;164(1-2):134-7. doi: 10.1093/rpd/ncu296. Epub 2014 Oct 1. Radiat Prot Dosimetry. 2015. PMID: 25274533
Genotoxic risk of ethyl-paraben could be related to telomere shortening.
Finot F, Kaddour A, Morat L, Mouche I, Zaguia N, Cuceu C, Souverville D, Négrault S, Cariou O, Essahli A, Prigent N, Saul J, Paillard F, Heidingsfelder L, Lafouge P, Al Jawhari M, Hempel WM, El May M, Colicchio B, Dieterlen A, Jeandidier E, Sabatier L, Clements J, M'Kacher R. Finot F, et al. Among authors: hempel wm. J Appl Toxicol. 2017 Jun;37(6):758-771. doi: 10.1002/jat.3425. Epub 2016 Dec 20. J Appl Toxicol. 2017. PMID: 27995640
Establishment and Characterization of a Reliable Xenograft Model of Hodgkin Lymphoma Suitable for the Study of Tumor Origin and the Design of New Therapies.
M'kacher R, Frenzel M, Al Jawhari M, Junker S, Cuceu C, Morat L, Bauchet AL, Stimmer L, Lenain A, Dechamps N, Hempel WM, Pottier G, Heidingsfelder L, Laplagne E, Borie C, Oudrhiri N, Jouni D, Bennaceur-Griscelli A, Colicchio B, Dieterlen A, Girinsky T, Boisgard R, Bourhis J, Bosq J, Mehrling T, Jeandidier E, Carde P. M'kacher R, et al. Among authors: hempel wm. Cancers (Basel). 2018 Oct 31;10(11):414. doi: 10.3390/cancers10110414. Cancers (Basel). 2018. PMID: 30384446 Free PMC article.
A new tool for genotoxic risk assessment: Reevaluation of the cytokinesis-block micronucleus assay using semi-automated scoring following telomere and centromere staining.
Zaguia N, Laplagne E, Colicchio B, Cariou O, Al Jawhari M, Heidingsfelder L, Hempel WM, Jrad BBH, Jeandidier E, Dieterlen A, Carde P, Voisin P, M'kacher R. Zaguia N, et al. Among authors: hempel wm. Mutat Res Genet Toxicol Environ Mutagen. 2020 Feb-Mar;850-851:503143. doi: 10.1016/j.mrgentox.2020.503143. Epub 2020 Jan 22. Mutat Res Genet Toxicol Environ Mutagen. 2020. PMID: 32247554
39 results