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Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells.
ACS Infect Dis. 2021 Jan 8;7(1):123-140. doi: 10.1021/acsinfecdis.0c00669. Epub 2020 Dec 3.
ACS Infect Dis. 2021.
PMID: 33269912
Free PMC article.
Inhibiting the BfrB:Bfd interaction in Pseudomonas aeruginosa causes irreversible iron accumulation in bacterioferritin and iron deficiency in the bacterial cytosol.
Eshelman K, Yao H, Punchi Hewage AND, Deay JJ, Chandler JR, Rivera M.
Eshelman K, et al. Among authors: punchi hewage and.
Metallomics. 2017 Jun 21;9(6):646-659. doi: 10.1039/c7mt00042a.
Metallomics. 2017.
PMID: 28318006
Free PMC article.
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Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity.
Punchi Hewage AND, Yao H, Nammalwar B, Gnanasekaran KK, Lovell S, Bunce RA, Eshelman K, Phaniraj SM, Lee MM, Peterson BR, Battaile KP, Reitz AB, Rivera M.
Punchi Hewage AND, et al.
J Am Chem Soc. 2019 May 22;141(20):8171-8184. doi: 10.1021/jacs.9b00394. Epub 2019 May 9.
J Am Chem Soc. 2019.
PMID: 31038945
Free PMC article.
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Mobilization of Iron Stored in Bacterioferritin Is Required for Metabolic Homeostasis in Pseudomonas aeruginosa.
Punchi Hewage AND, Fontenot L, Guidry J, Weldeghiorghis T, Mehta AK, Donnarumma F, Rivera M.
Punchi Hewage AND, et al.
Pathogens. 2020 Nov 24;9(12):980. doi: 10.3390/pathogens9120980.
Pathogens. 2020.
PMID: 33255203
Free PMC article.
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