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Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome.
Rom O, Liu Y, Liu Z, Zhao Y, Wu J, Ghrayeb A, Villacorta L, Fan Y, Chang L, Wang L, Liu C, Yang D, Song J, Rech JC, Guo Y, Wang H, Zhao G, Liang W, Koike Y, Lu H, Koike T, Hayek T, Pennathur S, Xi C, Wen B, Sun D, Garcia-Barrio MT, Aviram M, Gottlieb E, Mor I, Liu W, Zhang J, Chen YE. Rom O, et al. Among authors: chen ye. Sci Transl Med. 2020 Dec 2;12(572):eaaz2841. doi: 10.1126/scitranslmed.aaz2841. Sci Transl Med. 2020. PMID: 33268508 Free PMC article.
Molecular recognition of nitrated fatty acids by PPAR gamma.
Li Y, Zhang J, Schopfer FJ, Martynowski D, Garcia-Barrio MT, Kovach A, Suino-Powell K, Baker PR, Freeman BA, Chen YE, Xu HE. Li Y, et al. Among authors: chen ye. Nat Struct Mol Biol. 2008 Aug;15(8):865-7. doi: 10.1038/nsmb.1447. Epub 2008 Jul 6. Nat Struct Mol Biol. 2008. PMID: 18604218 Free PMC article.
PPARs and the cardiovascular system.
Hamblin M, Chang L, Fan Y, Zhang J, Chen YE. Hamblin M, et al. Among authors: chen ye. Antioxid Redox Signal. 2009 Jun;11(6):1415-52. doi: 10.1089/ars.2008.2280. Antioxid Redox Signal. 2009. PMID: 19061437 Free PMC article. Review.
Expression profiling of nuclear receptors in human and mouse embryonic stem cells.
Xie CQ, Jeong Y, Fu M, Bookout AL, Garcia-Barrio MT, Sun T, Kim BH, Xie Y, Root S, Zhang J, Xu RH, Chen YE, Mangelsdorf DJ. Xie CQ, et al. Among authors: chen ye. Mol Endocrinol. 2009 May;23(5):724-33. doi: 10.1210/me.2008-0465. Epub 2009 Feb 5. Mol Endocrinol. 2009. PMID: 19196830 Free PMC article.
Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions.
Schopfer FJ, Cole MP, Groeger AL, Chen CS, Khoo NK, Woodcock SR, Golin-Bisello F, Motanya UN, Li Y, Zhang J, Garcia-Barrio MT, Rudolph TK, Rudolph V, Bonacci G, Baker PR, Xu HE, Batthyany CI, Chen YE, Hallis TM, Freeman BA. Schopfer FJ, et al. Among authors: chen cs, chen ye. J Biol Chem. 2010 Apr 16;285(16):12321-33. doi: 10.1074/jbc.M109.091512. Epub 2010 Jan 22. J Biol Chem. 2010. PMID: 20097754 Free PMC article.
2,087 results