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Increased MAO-A Activity Promotes Progression of Pulmonary Arterial Hypertension.
Sun XQ, Peters EL, Schalij I, Axelsen JB, Andersen S, Kurakula K, Gomez-Puerto MC, Szulcek R, Pan X, da Silva Goncalves Bos D, Schiepers REJ, Andersen A, Goumans MJ, Vonk Noordegraaf A, van der Laarse WJ, de Man FS, Bogaard HJ. Sun XQ, et al. Among authors: pan x. Am J Respir Cell Mol Biol. 2021 Mar;64(3):331-343. doi: 10.1165/rcmb.2020-0105OC. Am J Respir Cell Mol Biol. 2021. PMID: 33264068
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension.
Rol N, de Raaf MA, Sun XQ, Kuiper VP, da Silva Gonçalves Bos D, Happé C, Kurakula K, Dickhoff C, Thuillet R, Tu L, Guignabert C, Schalij I, Lodder K, Pan X, Herrmann FE, van Nieuw Amerongen GP, Koolwijk P, Vonk-Noordegraaf A, de Man FS, Wollin L, Goumans MJ, Szulcek R, Bogaard HJ. Rol N, et al. Among authors: pan x. Cardiovasc Res. 2019 Feb 1;115(2):432-439. doi: 10.1093/cvr/cvy186. Cardiovasc Res. 2019. PMID: 30032282
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells.
Szulcek R, Sanchez-Duffhues G, Rol N, Pan X, Tsonaka R, Dickhoff C, Yung LM, Manz XD, Kurakula K, Kiełbasa SM, Mei H, Timens W, Yu PB, Bogaard HJ, Goumans MJ. Szulcek R, et al. Among authors: pan x. Angiogenesis. 2020 Nov;23(4):699-714. doi: 10.1007/s10456-020-09741-x. Epub 2020 Aug 19. Angiogenesis. 2020. PMID: 32813135 Free PMC article.
Epigenetic Modification of the von Willebrand Factor Promoter Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension.
Manz XD, Szulcek R, Pan X, Symersky P, Dickhoff C, Majolée J, Kremer V, Michielon E, Jordanova ES, Radonic T, Bijnsdorp IV, Piersma SR, Pham TV, Jimenez CR, Vonk Noordegraaf A, de Man FS, Boon RA, Voorberg J, Hordijk PL, Aman J, Bogaard HJ. Manz XD, et al. Among authors: pan x. Am J Respir Crit Care Med. 2022 Apr 1;205(7):806-818. doi: 10.1164/rccm.202109-2075OC. Am J Respir Crit Care Med. 2022. PMID: 35081007
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