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Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Yao H, Sun Y, Deng YQ, Wang N, Tan Y, Zhang NN, Li XF, Kong C, Xu YP, Chen Q, Cao TS, Zhao H, Yan X, Cao L, Lv Z, Zhu D, Feng R, Wu N, Zhang W, Hu Y, Chen K, Zhang RR, Lv Q, Sun S, Zhou Y, Yan R, Yang G, Sun X, Liu C, Lu X, Cheng L, Qiu H, Huang XY, Weng T, Shi D, Jiang W, Shao J, Wang L, Zhang J, Jiang T, Lang G, Qin CF, Li L, Wang X. Yao H, et al. Among authors: zhao h. Cell Res. 2021 Jan;31(1):25-36. doi: 10.1038/s41422-020-00444-y. Epub 2020 Dec 1. Cell Res. 2021. PMID: 33262452 Free PMC article.
A Thermostable mRNA Vaccine against COVID-19.
Zhang NN, Li XF, Deng YQ, Zhao H, Huang YJ, Yang G, Huang WJ, Gao P, Zhou C, Zhang RR, Guo Y, Sun SH, Fan H, Zu SL, Chen Q, He Q, Cao TS, Huang XY, Qiu HY, Nie JH, Jiang Y, Yan HY, Ye Q, Zhong X, Xue XL, Zha ZY, Zhou D, Yang X, Wang YC, Ying B, Qin CF. Zhang NN, et al. Among authors: zhao h. Cell. 2020 Sep 3;182(5):1271-1283.e16. doi: 10.1016/j.cell.2020.07.024. Epub 2020 Jul 23. Cell. 2020. PMID: 32795413 Free PMC article.
25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor.
Zu S, Deng YQ, Zhou C, Li J, Li L, Chen Q, Li XF, Zhao H, Gold S, He J, Li X, Zhang C, Yang H, Cheng G, Qin CF. Zu S, et al. Among authors: zhao h. Cell Res. 2020 Nov;30(11):1043-1045. doi: 10.1038/s41422-020-00398-1. Epub 2020 Aug 18. Cell Res. 2020. PMID: 32811977 Free PMC article. No abstract available.
Lipid nanoparticle-encapsulated mRNA antibody provides long-term protection against SARS-CoV-2 in mice and hamsters.
Deng YQ, Zhang NN, Zhang YF, Zhong X, Xu S, Qiu HY, Wang TC, Zhao H, Zhou C, Zu SL, Chen Q, Cao TS, Ye Q, Chi H, Duan XH, Lin DD, Zhang XJ, Xie LZ, Gao YW, Ying B, Qin CF. Deng YQ, et al. Among authors: zhao h. Cell Res. 2022 Apr;32(4):375-382. doi: 10.1038/s41422-022-00630-0. Epub 2022 Feb 24. Cell Res. 2022. PMID: 35210606 Free PMC article.
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