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Chronic High Glucose Concentration Induces Inflammatory and Remodeling Changes in Valvular Endothelial Cells and Valvular Interstitial Cells in a Gelatin Methacrylate 3D Model of the Human Aortic Valve.
Polymers (Basel). 2020 Nov 25;12(12):2786. doi: 10.3390/polym12122786.
Polymers (Basel). 2020.
PMID: 33255639
Free PMC article.
Molecular mechanisms involved in high glucose-induced valve calcification in a 3D valve model with human valvular cells.
Vadana M, Cecoltan S, Ciortan L, Macarie RD, Tucureanu MM, Mihaila AC, Droc I, Butoi E, Manduteanu I.
Vadana M, et al.
J Cell Mol Med. 2020 Jun;24(11):6350-6361. doi: 10.1111/jcmm.15277. Epub 2020 Apr 19.
J Cell Mol Med. 2020.
PMID: 32307869
Free PMC article.
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High Glucose Induced Changes in Human VEC Phenotype in a 3D Hydrogel Derived From Cell-Free Native Aortic Root.
Cecoltan S, Ciortan L, Macarie RD, Vadana M, Mihaila AC, Tucureanu M, Vlad ML, Droc I, Gherghiceanu M, Simionescu A, Simionescu DT, Butoi E, Manduteanu I.
Cecoltan S, et al. Among authors: vadana m.
Front Cardiovasc Med. 2021 Aug 12;8:714573. doi: 10.3389/fcvm.2021.714573. eCollection 2021.
Front Cardiovasc Med. 2021.
PMID: 34458339
Free PMC article.
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Parathyroid Hormone Induces Human Valvular Endothelial Cells Dysfunction That Impacts the Osteogenic Phenotype of Valvular Interstitial Cells.
Vadana M, Cecoltan S, Ciortan L, Macarie RD, Mihaila AC, Tucureanu MM, Gan AM, Simionescu M, Manduteanu I, Droc I, Butoi E.
Vadana M, et al.
Int J Mol Sci. 2022 Mar 29;23(7):3776. doi: 10.3390/ijms23073776.
Int J Mol Sci. 2022.
PMID: 35409134
Free PMC article.
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The expression of MMP-1 and MMP-9 is up-regulated by smooth muscle cells after their cross-talk with macrophages in high glucose conditions.
Macarie RD, Vadana M, Ciortan L, Tucureanu MM, Ciobanu A, Vinereanu D, Manduteanu I, Simionescu M, Butoi E.
Macarie RD, et al. Among authors: vadana m.
J Cell Mol Med. 2018 Sep;22(9):4366-4376. doi: 10.1111/jcmm.13728. Epub 2018 Jul 10.
J Cell Mol Med. 2018.
PMID: 29992758
Free PMC article.
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Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis.
Tucureanu MM, Filippi A, Alexandru N, Ana Constantinescu C, Ciortan L, Macarie R, Vadana M, Voicu G, Frunza S, Nistor D, Simionescu A, Simionescu DT, Georgescu A, Manduteanu I.
Tucureanu MM, et al. Among authors: vadana m.
Diab Vasc Dis Res. 2019 Nov;16(6):562-576. doi: 10.1177/1479164119874469. Epub 2019 Sep 18.
Diab Vasc Dis Res. 2019.
PMID: 31530180
Free PMC article.
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Transcriptional Profiling and Functional Analysis of N1/N2 Neutrophils Reveal an Immunomodulatory Effect of S100A9-Blockade on the Pro-Inflammatory N1 Subpopulation.
Mihaila AC, Ciortan L, Macarie RD, Vadana M, Cecoltan S, Preda MB, Hudita A, Gan AM, Jakobsson G, Tucureanu MM, Barbu E, Balanescu S, Simionescu M, Schiopu A, Butoi E.
Mihaila AC, et al. Among authors: vadana m.
Front Immunol. 2021 Aug 10;12:708770. doi: 10.3389/fimmu.2021.708770. eCollection 2021.
Front Immunol. 2021.
PMID: 34447377
Free PMC article.
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