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Human umbilical cord blood cells transfected with VEGF and L(1)CAM do not differentiate into neurons but transform into vascular endothelial cells and secrete neuro-trophic factors to support neuro-genesis-a novel approach in stem cell therapy.
Rizvanov AA, Kiyasov AP, Gaziziov IM, Yilmaz TS, Kaligin MS, Andreeva DI, Shafigullina AK, Guseva DS, Kiselev SL, Matin K, Palotás A, Islamov RR. Rizvanov AA, et al. Among authors: islamov rr. Neurochem Int. 2008 Dec;53(6-8):389-94. doi: 10.1016/j.neuint.2008.09.011. Epub 2008 Sep 26. Neurochem Int. 2008. PMID: 18948156
Genetically modified human umbilical cord blood cells expressing vascular endothelial growth factor and fibroblast growth factor 2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis transgenic mice.
Rizvanov AA, Guseva DS, Salafutdinov II, Kudryashova NV, Bashirov FV, Kiyasov AP, Yalvaç ME, Gazizov IM, Kaligin MS, Sahin F, Mukhamedyarov MA, Palotás A, Islamov RR. Rizvanov AA, et al. Among authors: islamov rr. Exp Biol Med (Maywood). 2011 Jan;236(1):91-8. doi: 10.1258/ebm.2010.010172. Epub 2010 Dec 16. Exp Biol Med (Maywood). 2011. PMID: 21163822 Free article.
Analysis of the efficiency of gene-cell therapy in transgenic mice with amyotrophic lateral sclerosis phenotype.
Mukhamedyarov MA, Rizvanov AA, Safiullov ZZ, Izmailov AA, Sharifullina GA, Solovieva VV, Fedotova VY, Salafutdinov II, Cherenkova EE, Bashirov FV, Kaligin MS, Abdulkhakov SR, Shmarov MM, Logunov DY, Naroditsky BS, Kiyasov AP, Zefirov AL, Islamov RR. Mukhamedyarov MA, et al. Among authors: islamov rr. Bull Exp Biol Med. 2013 Feb;154(4):558-61. doi: 10.1007/s10517-013-1999-2. Bull Exp Biol Med. 2013. PMID: 23486603 Free article. English, Russian.
Characterization of spinal cord glial cells in a model of hindlimb unloading in mice.
Chelyshev YA, Muhamedshina YO, Povysheva TV, Shaymardanova GF, Rizvanov AA, Nigmetzyanova MV, Tiapkina OV, Bondarenko NI, Nikolskiy EE, Islamov RR. Chelyshev YA, et al. Among authors: islamov rr. Neuroscience. 2014 Nov 7;280:328-39. doi: 10.1016/j.neuroscience.2014.09.004. Epub 2014 Sep 16. Neuroscience. 2014. PMID: 25218808
Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule.
Islamov RR, Rizvanov AA, Mukhamedyarov MA, Salafutdinov II, Garanina EE, Fedotova VY, Solovyeva VV, Mukhamedshina YO, Safiullov ZZ, Izmailov AA, Guseva DS, Zefirov AL, Kiyasov AP, Palotas A. Islamov RR, et al. Curr Gene Ther. 2015;15(3):266-76. doi: 10.2174/1566523215666150126122317. Curr Gene Ther. 2015. PMID: 25619885
Adenoviral vector carrying glial cell-derived neurotrophic factor for direct gene therapy in comparison with human umbilical cord blood cell-mediated therapy of spinal cord injury in rat.
Mukhamedshina YO, Shaymardanova GF, Garanina ЕЕ, Salafutdinov II, Rizvanov АА, Islamov RR, Chelyshev YA. Mukhamedshina YO, et al. Among authors: islamov rr. Spinal Cord. 2016 May;54(5):347-59. doi: 10.1038/sc.2015.161. Epub 2015 Sep 29. Spinal Cord. 2016. PMID: 26415641
93 results