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Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control.
Salpini R, Alkhatib M, Costa G, Piermatteo L, Ambrosio FA, Di Maio VC, Scutari R, Duca L, Berno G, Fabeni L, Alcaro S, Ceccherini-Silberstein F, Artese A, Svicher V. Salpini R, et al. Among authors: svicher v. J Antimicrob Chemother. 2021 Jan 19;76(2):396-412. doi: 10.1093/jac/dkaa444. J Antimicrob Chemother. 2021. PMID: 33254234 Free PMC article.
Limited development and progression of resistance of HIV-1 to the nucleoside analogue reverse transcriptase inhibitor lamivudine in human primary macrophages.
Aquaro S, Svicher V, Ceccherini-Silberstein F, Cenci A, Marcuccilli F, Giannella S, Marcon L, Caliò R, Balzarini J, Perno CF. Aquaro S, et al. Among authors: svicher v. J Antimicrob Chemother. 2005 Jun;55(6):872-8. doi: 10.1093/jac/dki104. Epub 2005 Apr 21. J Antimicrob Chemother. 2005. PMID: 15845785
High sequence conservation of human immunodeficiency virus type 1 reverse transcriptase under drug pressure despite the continuous appearance of mutations.
Ceccherini-Silberstein F, Gago F, Santoro M, Gori C, Svicher V, Rodríguez-Barrios F, d'Arrigo R, Ciccozzi M, Bertoli A, d'Arminio Monforte A, Balzarini J, Antinori A, Perno CF. Ceccherini-Silberstein F, et al. Among authors: svicher v. J Virol. 2005 Aug;79(16):10718-29. doi: 10.1128/JVI.79.16.10718-10729.2005. J Virol. 2005. PMID: 16051864 Free PMC article.
Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors.
Svicher V, Sing T, Santoro MM, Forbici F, Rodríguez-Barrios F, Bertoli A, Beerenwinkel N, Bellocchi MC, Gago F, d'Arminio Monforte A, Antinori A, Lengauer T, Ceccherini-Silberstein F, Perno CF. Svicher V, et al. J Virol. 2006 Jul;80(14):7186-98. doi: 10.1128/JVI.02084-05. J Virol. 2006. PMID: 16809324 Free PMC article.
Temporal characterization of drug resistance associated mutations in HIV-1 protease and reverse transcriptase in patients failing antiretroviral therapy.
Santoro MM, Svicher V, Gori C, Zaccarelli M, Tozzi V, Forbici F, D'Arrigo R, Trotta MP, Bellocchi MC, Visco-Comandini U, Cenci A, Bertoli A, Narciso P, Antinori A, Perno CF, Ceccherini-Silberstein F. Santoro MM, et al. Among authors: svicher v. New Microbiol. 2006 Apr;29(2):89-100. New Microbiol. 2006. PMID: 16841549
Specific mutations in HIV-1 gp41 are associated with immunological success in HIV-1-infected patients receiving enfuvirtide treatment.
Aquaro S, D'Arrigo R, Svicher V, Perri GD, Caputo SL, Visco-Comandini U, Santoro M, Bertoli A, Mazzotta F, Bonora S, Tozzi V, Bellagamba R, Zaccarelli M, Narciso P, Antinori A, Perno CF. Aquaro S, et al. Among authors: svicher v. J Antimicrob Chemother. 2006 Oct;58(4):714-22. doi: 10.1093/jac/dkl306. Epub 2006 Aug 5. J Antimicrob Chemother. 2006. PMID: 16891628
Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of resistance to nonnucleoside inhibitors.
Ceccherini-Silberstein F, Svicher V, Sing T, Artese A, Santoro MM, Forbici F, Bertoli A, Alcaro S, Palamara G, d'Arminio Monforte A, Balzarini J, Antinori A, Lengauer T, Perno CF. Ceccherini-Silberstein F, et al. Among authors: svicher v. J Virol. 2007 Oct;81(20):11507-19. doi: 10.1128/JVI.00303-07. Epub 2007 Aug 8. J Virol. 2007. PMID: 17686836 Free PMC article.
150 results