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Page 1
Nanoscale Pattern Extraction from Relative Positions of Sparse 3D Localizations.
Curd AP, Leng J, Hughes RE, Cleasby AJ, Rogers B, Trinh CH, Baird MA, Takagi Y, Tiede C, Sieben C, Manley S, Schlichthaerle T, Jungmann R, Ries J, Shroff H, Peckham M. Curd AP, et al. Among authors: tiede c. Nano Lett. 2021 Feb 10;21(3):1213-1220. doi: 10.1021/acs.nanolett.0c03332. Epub 2020 Nov 30. Nano Lett. 2021. PMID: 33253583 Free PMC article.
Affimer proteins are versatile and renewable affinity reagents.
Tiede C, Bedford R, Heseltine SJ, Smith G, Wijetunga I, Ross R, AlQallaf D, Roberts AP, Balls A, Curd A, Hughes RE, Martin H, Needham SR, Zanetti-Domingues LC, Sadigh Y, Peacock TP, Tang AA, Gibson N, Kyle H, Platt GW, Ingram N, Taylor T, Coletta LP, Manfield I, Knowles M, Bell S, Esteves F, Maqbool A, Prasad RK, Drinkhill M, Bon RS, Patel V, Goodchild SA, Martin-Fernandez M, Owens RJ, Nettleship JE, Webb ME, Harrison M, Lippiat JD, Ponnambalam S, Peckham M, Smith A, Ferrigno PK, Johnson M, McPherson MJ, Tomlinson DC. Tiede C, et al. Elife. 2017 Jun 27;6:e24903. doi: 10.7554/eLife.24903. Elife. 2017. PMID: 28654419 Free PMC article.
Alternative reagents to antibodies in imaging applications.
Bedford R, Tiede C, Hughes R, Curd A, McPherson MJ, Peckham M, Tomlinson DC. Bedford R, et al. Among authors: tiede c. Biophys Rev. 2017 Aug;9(4):299-308. doi: 10.1007/s12551-017-0278-2. Epub 2017 Jul 27. Biophys Rev. 2017. PMID: 28752365 Free PMC article. Review.
Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.
Hughes DJ, Tiede C, Penswick N, Tang AA, Trinh CH, Mandal U, Zajac KZ, Gaule T, Howell G, Edwards TA, Duan J, Feyfant E, McPherson MJ, Tomlinson DC, Whitehouse A. Hughes DJ, et al. Among authors: tiede c. Sci Signal. 2017 Nov 14;10(505):eaaj2005. doi: 10.1126/scisignal.aaj2005. Sci Signal. 2017. PMID: 29138295 Free PMC article.
Site-Specific Labeling of Affimers for DNA-PAINT Microscopy.
Schlichthaerle T, Eklund AS, Schueder F, Strauss MT, Tiede C, Curd A, Ries J, Peckham M, Tomlinson DC, Jungmann R. Schlichthaerle T, et al. Among authors: tiede c. Angew Chem Int Ed Engl. 2018 Aug 20;57(34):11060-11063. doi: 10.1002/anie.201804020. Epub 2018 Jul 15. Angew Chem Int Ed Engl. 2018. PMID: 29873161 Free article.
Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests.
Álvarez-Rodríguez B, Tiede C, Hoste ACR, Surtees RA, Trinh CH, Slack GS, Chamberlain J, Hewson R, Fresco A, Sastre P, Tomlinson DC, Millner PA, Edwards TA, Barr JN. Álvarez-Rodríguez B, et al. Among authors: tiede c. PLoS Negl Trop Dis. 2020 Jun 3;14(6):e0008364. doi: 10.1371/journal.pntd.0008364. eCollection 2020 Jun. PLoS Negl Trop Dis. 2020. PMID: 32492018 Free PMC article.
Affimer-mediated locking of p21-activated kinase 5 in an intermediate activation state results in kinase inhibition.
Martin HL, Turner AL, Higgins J, Tang AA, Tiede C, Taylor T, Siripanthong S, Adams TL, Manfield IW, Bell SM, Morrison EE, Bond J, Trinh CH, Hurst CD, Knowles MA, Bayliss RW, Tomlinson DC. Martin HL, et al. Among authors: tiede c. Cell Rep. 2023 Oct 31;42(10):113184. doi: 10.1016/j.celrep.2023.113184. Epub 2023 Sep 29. Cell Rep. 2023. PMID: 37776520 Free article.
RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site.
Haza KZ, Martin HL, Rao A, Turner AL, Saunders SE, Petersen B, Tiede C, Tipping K, Tang AA, Ajayi M, Taylor T, Harvey M, Fishwick KM, Adams TL, Gaule TG, Trinh CH, Johnson M, Breeze AL, Edwards TA, McPherson MJ, Tomlinson DC. Haza KZ, et al. Among authors: tiede c. Nat Commun. 2021 Jun 30;12(1):4045. doi: 10.1038/s41467-021-24316-0. Nat Commun. 2021. PMID: 34193876 Free PMC article.
45 results