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509 results

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Page 1
Identification and Mechanistic Characterization of a Peptide Inhibitor of Glycogen Synthase Kinase (GSK3β) Derived from the Disrupted in Schizophrenia 1 (DISC1) Protein.
Saundh SL, Patnaik D, Gagné S, Bishop JA, Lipsit S, Amat S, Pujari N, Nambisan AK, Bigsby R, Murphy M, Tsai LH, Haggarty SJ, Leung AK. Saundh SL, et al. Among authors: bishop ja. ACS Chem Neurosci. 2020 Dec 16;11(24):4128-4138. doi: 10.1021/acschemneuro.0c00380. Epub 2020 Nov 30. ACS Chem Neurosci. 2020. PMID: 33253521
Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects.
Wagner FF, Bishop JA, Gale JP, Shi X, Walk M, Ketterman J, Patnaik D, Barker D, Walpita D, Campbell AJ, Nguyen S, Lewis M, Ross L, Weïwer M, An WF, Germain AR, Nag PP, Metkar S, Kaya T, Dandapani S, Olson DE, Barbe AL, Lazzaro F, Sacher JR, Cheah JH, Fei D, Perez J, Munoz B, Palmer M, Stegmaier K, Schreiber SL, Scolnick E, Zhang YL, Haggarty SJ, Holson EB, Pan JQ. Wagner FF, et al. Among authors: bishop ja. ACS Chem Biol. 2016 Jul 15;11(7):1952-63. doi: 10.1021/acschembio.6b00306. Epub 2016 May 13. ACS Chem Biol. 2016. PMID: 27128528
Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion.
Zhao WN, Tobe BTD, Udeshi ND, Xuan LL, Pernia CD, Zolg DP, Roberts AJ, Mani D, Blumenthal SR, Kurtser I, Patnaik D, Gaisina I, Bishop J, Sheridan SD, Lalonde J, Carr SA, Snyder EY, Haggarty SJ. Zhao WN, et al. Transl Psychiatry. 2020 Feb 24;10(1):76. doi: 10.1038/s41398-020-0753-6. Transl Psychiatry. 2020. PMID: 32094324 Free PMC article.
Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3β.
Wang Y, Wach JY, Sheehan P, Zhong C, Zhan C, Harris R, Almo SC, Bishop J, Haggarty SJ, Ramek A, Berry KN, O'Herin C, Koehler AN, Hung AW, Young DW. Wang Y, et al. ACS Med Chem Lett. 2016 Jul 14;7(9):852-6. doi: 10.1021/acsmedchemlett.6b00230. eCollection 2016 Sep 8. ACS Med Chem Lett. 2016. PMID: 27660690 Free PMC article.
Drug discovery for psychiatric disorders using high-content single-cell screening of signaling network responses ex vivo.
Lago SG, Tomasik J, van Rees GF, Steeb H, Cox DA, Rustogi N, Ramsey JM, Bishop JA, Petryshen T, Haggarty SJ, Vázquez-Bourgon J, Papiol S, Suarez-Pinilla P, Crespo-Facorro B, van Beveren NJ, Bahn S. Lago SG, et al. Among authors: bishop ja. Sci Adv. 2019 May 8;5(5):eaau9093. doi: 10.1126/sciadv.aau9093. eCollection 2019 May. Sci Adv. 2019. PMID: 31086815 Free PMC article.
Playing editorial catch up.
Bishop JA. Bishop JA. Semin Diagn Pathol. 2024 May 21:S0740-2570(24)00047-9. doi: 10.1053/j.semdp.2024.05.002. Online ahead of print. Semin Diagn Pathol. 2024. PMID: 38782648 Review. No abstract available.
509 results