Perumal Y - Search Results

1

Synthesis of novel cytotoxic tetracyclic acridone derivatives and study of their molecular docking, ADMET, QSAR, bioactivity and protein binding properties.

Veligeti R, Madhu RB, Anireddy J, Pasupuleti VR, Avula VKR, Ethiraj KS, Uppalanchi S, Kasturi S, Perumal Y, Anantaraju HS, Polkam N, Guda MR, Vallela S, Zyryanov GV. Veligeti R, et al. Among authors: perumal y. Sci Rep. 2020 Nov 26;10(1):20720. doi: 10.1038/s41598-020-77590-1. Sci Rep. 2020. PMID: 33244007 Free PMC article.

2

Synthesis, in vitro anticancer and antimycobacterial evaluation of new 5-(2,5-dimethoxyphenyl)-1,3,4-thiadiazole-2-amino derivatives.

Polkam N, Rayam P, Anireddy JS, Yennam S, Anantaraju HS, Dharmarajan S, Perumal Y, Kotapalli SS, Ummanni R, Balasubramanian S. Polkam N, et al. Among authors: perumal y. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1398-402. doi: 10.1016/j.bmcl.2015.02.052. Epub 2015 Feb 27. Bioorg Med Chem Lett. 2015. PMID: 25765907

3

Synthesis, molecular properties prediction and anticancer, antioxidant evaluation of new edaravone derivatives.

Polkam N, Ramaswamy VR, Rayam P, Allaka TR, Anantaraju HS, Dharmarajan S, Perumal Y, Gandamalla D, Yellu NR, Balasubramanian S, Anireddy JS. Polkam N, et al. Among authors: perumal y. Bioorg Med Chem Lett. 2016 May 15;26(10):2562-2568. doi: 10.1016/j.bmcl.2016.03.024. Epub 2016 Mar 9. Bioorg Med Chem Lett. 2016. PMID: 27055942

4

Synthesis and α-glucosidase inhibition activity of dihydroxy pyrrolidines.

Kasturi S, Surarapu S, Uppalanchi S, Anireddy JS, Dwivedi S, Anantaraju HS, Perumal Y, Sigalapalli DK, Babu BN, Ethiraj KS. Kasturi S, et al. Among authors: perumal y. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2818-2823. doi: 10.1016/j.bmcl.2017.04.078. Epub 2017 May 2. Bioorg Med Chem Lett. 2017. PMID: 28495082

5

Synthesis, molecular modeling and biological evaluation of aza-flavanones as α-glucosidase inhibitors.

Kasturi S, Surarapu S, Bathoju CC, Uppalanchi S, Dwivedi S, Perumal Y, Sigalapalli DK, Babu BN, Ethiraj KS, Anireddy JS. Kasturi S, et al. Among authors: perumal y. Medchemcomm. 2017 Jun 14;8(8):1618-1630. doi: 10.1039/c7md00162b. eCollection 2017 Aug 1. Medchemcomm. 2017. PMID: 30108873 Free PMC article.

6

Antimycobacterial and phototoxic evaluation of novel 6-fluoro/nitro-4-oxo-7-(sub)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid.

Murugesan D, Palaniappan S, Perumal Y, Arnab C, Valakunja N, Sriram D. Murugesan D, et al. Among authors: perumal y. Int J Antimicrob Agents. 2008 Apr;31(4):337-44. doi: 10.1016/j.ijantimicag.2007.12.007. Int J Antimicrob Agents. 2008. PMID: 18359434

7

A facile synthesis and discovery of highly functionalized tetrahydro-pyridines and pyridines as antimycobacterial agents.

Raju SK, Stephen MR, Subbu P, Debjani B, Perumal Y, Dharmarajan S. Raju SK, et al. Among authors: perumal y. Chem Pharm Bull (Tokyo). 2010 May;58(5):602-10. doi: 10.1248/cpb.58.602. Chem Pharm Bull (Tokyo). 2010. PMID: 20460783 Free article.

8

Combined inhibition of PDE4 and PI3Kδ modulates the inflammatory component involved in the progression of chronic obstructive pulmonary disease.

Dinavahi SS, Nyayapathy S, Perumal Y, Dharmarajan S, Viswanadha S. Dinavahi SS, et al. Among authors: perumal y. Drug Res (Stuttg). 2014 Apr;64(4):214-9. doi: 10.1055/s-0033-1355411. Epub 2013 Oct 8. Drug Res (Stuttg). 2014. PMID: 24105104

9

Design, synthesis and anti-mycobacterial activity of 1,2,3,5-tetrasubstituted pyrrolyl-N-acetic acid derivatives.

Pagadala LR, Mukkara LD, Singireddi S, Singh A, Thummaluru VR, Jagarlamudi PS, Guttala RS, Perumal Y, Dharmarajan S, Upadhyayula SM, Ummanni R, Basireddy VS, Ravirala N. Pagadala LR, et al. Among authors: perumal y. Eur J Med Chem. 2014 Sep 12;84:118-26. doi: 10.1016/j.ejmech.2014.06.075. Epub 2014 Jul 1. Eur J Med Chem. 2014. PMID: 25016370

10

A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro.

Dinavahi SS, Prasanna R, Dharmarajan S, Perumal Y, Viswanadha S. Dinavahi SS, et al. Among authors: perumal y. Cancer Res Treat. 2015 Oct;47(4):913-20. doi: 10.4143/crt.2014.057. Epub 2015 Jan 2. Cancer Res Treat. 2015. PMID: 25687876 Free PMC article.

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