Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis.
Tynan A, Mawhinney L, Armstrong ME, O'Reilly C, Kennedy S, Caraher E, Jülicher K, O'Dwyer D, Maher L, Schaffer K, Fabre A, McKone EF, Leng L, Bucala R, Bernhagen J, Cooke G, Donnelly SC.
Tynan A, et al.
FASEB J. 2017 Nov;31(11):5102-5110. doi: 10.1096/fj.201700463R. Epub 2017 Aug 2.
FASEB J. 2017.
PMID: 28768722
Free PMC article.
Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator that we have previously shown to be associated with an aggressive clinical phenotype in cystic fibrosis. ...Our novel findings support the concept of an anti-MIF strategy that targets this enzym …
Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator that we have previously shown to be associated with an …