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Aerosolized drug-loaded nanoparticles targeting migration inhibitory factors inhibit Pseudomonas aeruginosa-induced inflammation and biofilm formation.
Doroudian M, O'Neill A, O'Reilly C, Tynan A, Mawhinney L, McElroy A, Webster SS, MacLoughlin R, Volkov Y, E Armstrong M, A O'Toole G, Prina-Mello A, C Donnelly S. Doroudian M, et al. Among authors: a o toole g, tynan a. Nanomedicine (Lond). 2020 Dec;15(30):2933-2953. doi: 10.2217/nnm-2020-0344. Epub 2020 Nov 26. Nanomedicine (Lond). 2020. PMID: 33241979 Free PMC article.
Macrophage migration inhibitory factor (MIF) enzymatic activity and lung cancer.
Mawhinney L, Armstrong ME, O' Reilly C, Bucala R, Leng L, Fingerle-Rowson G, Fayne D, Keane MP, Tynan A, Maher L, Cooke G, Lloyd D, Conroy H, Donnelly SC. Mawhinney L, et al. Among authors: tynan a. Mol Med. 2015 Apr 16;20(1):729-35. doi: 10.2119/molmed.2014.00136. Mol Med. 2015. PMID: 25826675 Free PMC article.
Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis.
Tynan A, Mawhinney L, Armstrong ME, O'Reilly C, Kennedy S, Caraher E, Jülicher K, O'Dwyer D, Maher L, Schaffer K, Fabre A, McKone EF, Leng L, Bucala R, Bernhagen J, Cooke G, Donnelly SC. Tynan A, et al. FASEB J. 2017 Nov;31(11):5102-5110. doi: 10.1096/fj.201700463R. Epub 2017 Aug 2. FASEB J. 2017. PMID: 28768722 Free PMC article.
Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator that we have previously shown to be associated with an aggressive clinical phenotype in cystic fibrosis. ...Our novel findings support the concept of an anti-MIF strategy that targets this enzym …
Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator that we have previously shown to be associated with an …
Sarcoidosis, alveolar β-actin and pulmonary fibrosis.
Cooke G, Govender P, Watson CJ, Armstrong ME, O'Dwyer DN, Keane MP, King R, Tynan A, Dunn M, Donnelly SC. Cooke G, et al. Among authors: tynan a. QJM. 2013 Oct;106(10):897-902. doi: 10.1093/qjmed/hct160. Epub 2013 Jul 30. QJM. 2013. PMID: 23904517
[No title available]
[No authors listed] [No authors listed] PMID: 35557082
102 results