Tam YYC - Search Results

1

Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles.

Kulkarni JA , Thomson SB , Zaifman J , Leung J , Wagner PK , Hill A , Tam YYC , Cullis PR , Petkau TL , Leavitt BR . Kulkarni JA , et al. Among authors: tam yyc. Nanoscale. 2020 Dec 21;12(47):23959-23966. doi: 10.1039/d0nr06816k. Epub 2020 Nov 26. Nanoscale. 2020. PMID: 33241838

2

Synthesis of a labeled RGD-lipid, its incorporation into liposomal nanoparticles, and their trafficking in cultured endothelial cells.

Cressman S, Dobson I, Lee JB, Tam YY, Cullis PR. Cressman S, et al. Bioconjug Chem. 2009 Jul;20(7):1404-11. doi: 10.1021/bc900041f. Bioconjug Chem. 2009. PMID: 19534457

3

Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.

Basha G, Novobrantseva TI, Rosin N, Tam YY, Hafez IM, Wong MK, Sugo T, Ruda VM, Qin J, Klebanov B, Ciufolini M, Akinc A, Tam YK, Hope MJ, Cullis PR. Basha G, et al. Mol Ther. 2011 Dec;19(12):2186-200. doi: 10.1038/mt.2011.190. Epub 2011 Oct 4. Mol Ther. 2011. PMID: 21971424 Free PMC article.

4

Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo.

Lee JB, Zhang K, Tam YY, Tam YK, Belliveau NM, Sung VY, Lin PJ, LeBlanc E, Ciufolini MA, Rennie PS, Cullis PR. Lee JB, et al. Int J Cancer. 2012 Sep 1;131(5):E781-90. doi: 10.1002/ijc.27361. Epub 2012 Jan 3. Int J Cancer. 2012. PMID: 22095615 Free article.

5

Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA.

Lin PJ, Tam YY, Hafez I, Sandhu A, Chen S, Ciufolini MA, Nabi IR, Cullis PR. Lin PJ, et al. Nanomedicine. 2013 Feb;9(2):233-46. doi: 10.1016/j.nano.2012.05.019. Epub 2012 Jun 12. Nanomedicine. 2013. PMID: 22698807

6

Small molecule ligands for enhanced intracellular delivery of lipid nanoparticle formulations of siRNA.

Tam YY, Chen S, Zaifman J, Tam YK, Lin PJ, Ansell S, Roberge M, Ciufolini MA, Cullis PR. Tam YY, et al. Nanomedicine. 2013 Jul;9(5):665-74. doi: 10.1016/j.nano.2012.11.006. Epub 2012 Dec 6. Nanomedicine. 2013. PMID: 23219877

7

Advances in Lipid Nanoparticles for siRNA Delivery.

Tam YY, Chen S, Cullis PR. Tam YY, et al. Pharmaceutics. 2013 Sep 18;5(3):498-507. doi: 10.3390/pharmaceutics5030498. Pharmaceutics. 2013. PMID: 24300520 Free PMC article.

8

Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles.

Mui BL, Tam YK, Jayaraman M, Ansell SM, Du X, Tam YY, Lin PJ, Chen S, Narayanannair JK, Rajeev KG, Manoharan M, Akinc A, Maier MA, Cullis P, Madden TD, Hope MJ. Mui BL, et al. Mol Ther Nucleic Acids. 2013 Dec 17;2(12):e139. doi: 10.1038/mtna.2013.66. Mol Ther Nucleic Acids. 2013. PMID: 24345865 Free PMC article.

9

IGFBP2 is neither sufficient nor necessary for the physiological actions of leptin on glucose homeostasis in male ob/ob mice.

Neumann UH, Chen S, Tam YY, Baker RK, Covey SD, Cullis PR, Kieffer TJ. Neumann UH, et al. Endocrinology. 2014 Mar;155(3):716-25. doi: 10.1210/en.2013-1622. Epub 2014 Jan 1. Endocrinology. 2014. PMID: 24424049

10

Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration.

Chen S, Tam YY, Lin PJ, Leung AK, Tam YK, Cullis PR. Chen S, et al. J Control Release. 2014 Dec 28;196:106-12. doi: 10.1016/j.jconrel.2014.09.025. Epub 2014 Oct 5. J Control Release. 2014. PMID: 25285610

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