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Dysregulated immunity in SARS-CoV-2 infected pregnant women.
Sherer ML, Lei J, Creisher P, Jang M, Reddy R, Voegtline K, Olson S, Littlefield K, Park HS, Ursin RL, Ganesan A, Boyer T, Brown DM, Walch SN, Antar AAR, Manabe YC, Jones-Beatty K, Golden WC, Satin AJ, Sheffield JS, Pekosz A, Klein SL, Burd I. Sherer ML, et al. Among authors: littlefield k. medRxiv [Preprint]. 2020 Nov 16:2020.11.13.20231373. doi: 10.1101/2020.11.13.20231373. medRxiv. 2020. PMID: 33236024 Free PMC article. Preprint.
Durable SARS-CoV-2 B cell immunity after mild or severe disease.
Ogega CO, Skinner NE, Blair PW, Park HS, Littlefield K, Ganesan A, Ladiwala P, Antar AA, Ray SC, Betenbaugh MJ, Pekosz A, Klein SL, Manabe YC, Cox AL, Bailey JR. Ogega CO, et al. Among authors: littlefield k. medRxiv [Preprint]. 2020 Oct 30:2020.10.28.20220996. doi: 10.1101/2020.10.28.20220996. medRxiv. 2020. PMID: 33140070 Free PMC article. Updated. Preprint.
Delayed rise of oral fluid antibodies, elevated BMI, and absence of early fever correlate with longer time to SARS-CoV-2 RNA clearance in an longitudinally sampled cohort of COVID-19 outpatients.
Antar AAR, Yu T, Pisanic N, Azamfirei R, Tornheim JA, Brown DM, Kruczynski K, Hardick JP, Sewell T, Jang M, Church T, Walch SN, Reuland C, Bachu VS, Littlefield K, Park HS, Ursin RL, Ganesan A, Kusemiju O, Barnaba B, Charles C, Prizzi M, Johnstone JR, Payton C, Dai W, Fuchs J, Massaccesi G, Armstrong DT, Townsend JL, Keller SC, Demko ZO, Hu C, Wang MC, Sauer LM, Mostafa HH, Keruly JC, Mehta SH, Klein SL, Cox AL, Pekosz A, Heaney CD, Thomas DL, Blair PW, Manabe YC. Antar AAR, et al. Among authors: littlefield k. medRxiv [Preprint]. 2021 Mar 3:2021.03.02.21252420. doi: 10.1101/2021.03.02.21252420. medRxiv. 2021. PMID: 33688688 Free PMC article. Updated. Preprint.
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.
Klein S, Pekosz A, Park HS, Ursin R, Shapiro J, Benner S, Littlefield K, Kumar S, Naik HM, Betenbaugh M, Shrestha R, Wu A, Hughes R, Burgess I, Caturegli P, Laeyendecker O, Quinn T, Sullivan D, Shoham S, Redd A, Bloch E, Casadevall A, Tobian A. Klein S, et al. Among authors: littlefield k. medRxiv [Preprint]. 2020 Jun 28:2020.06.26.20139063. doi: 10.1101/2020.06.26.20139063. medRxiv. 2020. PMID: 32607519 Free PMC article. Updated. Preprint.
Durable SARS-CoV-2 B cell immunity after mild or severe disease.
Ogega CO, Skinner NE, Blair PW, Park HS, Littlefield K, Ganesan A, Dhakal S, Ladiwala P, Antar AA, Ray SC, Betenbaugh MJ, Pekosz A, Klein SL, Manabe YC, Cox AL, Bailey JR. Ogega CO, et al. Among authors: littlefield k. J Clin Invest. 2021 Apr 1;131(7):e145516. doi: 10.1172/JCI145516. J Clin Invest. 2021. PMID: 33571162 Free PMC article.
Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection.
Sherer ML, Lei J, Creisher PS, Jang M, Reddy R, Voegtline K, Olson S, Littlefield K, Park HS, Ursin RL, Ganesan A, Boyer T, Elsayed N, Brown DM, Walch SN, Antar AAR, Manabe YC, Jones-Beatty K, Golden WC, Satin AJ, Sheffield JS, Pekosz A, Klein SL, Burd I. Sherer ML, et al. Among authors: littlefield k. Am J Obstet Gynecol. 2021 Sep;225(3):301.e1-301.e14. doi: 10.1016/j.ajog.2021.03.028. Epub 2021 Mar 30. Am J Obstet Gynecol. 2021. PMID: 33798476 Free PMC article.
Delayed Rise of Oral Fluid Antibodies, Elevated BMI, and Absence of Early Fever Correlate With Longer Time to SARS-CoV-2 RNA Clearance in a Longitudinally Sampled Cohort of COVID-19 Outpatients.
Antar AAR, Yu T, Pisanic N, Azamfirei R, Tornheim JA, Brown DM, Kruczynski K, Hardick JP, Sewell T, Jang M, Church T, Walch SN, Reuland C, Bachu VS, Littlefield K, Park HS, Ursin RL, Ganesan A, Kusemiju O, Barnaba B, Charles C, Prizzi M, Johnstone JR, Payton C, Dai W, Fuchs J, Massaccesi G, Armstrong DT, Townsend JL, Keller SC, Demko ZO, Hu C, Wang MC, Sauer LM, Mostafa HH, Keruly JC, Mehta SH, Klein SL, Cox AL, Pekosz A, Heaney CD, Thomas DL, Blair PW, Manabe YC. Antar AAR, et al. Among authors: littlefield k. Open Forum Infect Dis. 2021 Apr 16;8(6):ofab195. doi: 10.1093/ofid/ofab195. eCollection 2021 Jun. Open Forum Infect Dis. 2021. PMID: 34095338 Free PMC article.
Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers.
Patel EU, Bloch EM, Clarke W, Hsieh YH, Boon D, Eby Y, Fernandez RE, Baker OR, Keruly M, Kirby CS, Klock E, Littlefield K, Miller J, Schmidt HA, Sullivan P, Piwowar-Manning E, Shrestha R, Redd AD, Rothman RE, Sullivan D, Shoham S, Casadevall A, Quinn TC, Pekosz A, Tobian AAR, Laeyendecker O. Patel EU, et al. Among authors: littlefield k. medRxiv [Preprint]. 2020 Sep 2:2020.08.31.20184788. doi: 10.1101/2020.08.31.20184788. medRxiv. 2020. PMID: 32908987 Free PMC article. Updated. Preprint.
SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy.
Natarajan H, Crowley AR, Butler SE, Xu S, Weiner JA, Bloch EM, Littlefield K, Wieland-Alter W, Connor RI, Wright PF, Benner SE, Bonny TS, Laeyendecker O, Sullivan D, Shoham S, Quinn TC, Larman HB, Casadevall A, Pekosz A, Redd AD, Tobian AAR, Ackerman ME. Natarajan H, et al. Among authors: littlefield k. medRxiv [Preprint]. 2020 Sep 18:2020.09.16.20196154. doi: 10.1101/2020.09.16.20196154. medRxiv. 2020. PMID: 32995801 Free PMC article. Updated. Preprint.
Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers.
Heaney CD, Pisanic N, Randad PR, Kruczynski K, Howard T, Zhu X, Littlefield K, Patel EU, Shrestha R, Laeyendecker O, Shoham S, Sullivan D, Gebo K, Hanley D, Redd AD, Quinn TC, Casadevall A, Zenilman JM, Pekosz A, Bloch EM, Tobian AAR. Heaney CD, et al. Among authors: littlefield k. medRxiv [Preprint]. 2021 Feb 1:2021.01.28.21250717. doi: 10.1101/2021.01.28.21250717. medRxiv. 2021. PMID: 33532806 Free PMC article. Updated. Preprint.
62 results