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Human Thymic CD10+ PD-1+ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a- CD95+ CD28- CCR7- Developmental Stage.
Billiet L, Goetgeluk G, Bonte S, De Munter S, De Cock L, Pille M, Ingels J, Jansen H, Weening K, Van Nieuwerburgh F, Kerre T, Taghon T, Leclercq G, Vandekerckhove B. Billiet L, et al. Among authors: van nieuwerburgh f. Int J Mol Sci. 2020 Nov 20;21(22):8785. doi: 10.3390/ijms21228785. Int J Mol Sci. 2020. PMID: 33233766 Free PMC article.
The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation.
Taveirne S, Wahlen S, Van Loocke W, Kiekens L, Persyn E, Van Ammel E, De Mulder K, Roels J, Tilleman L, Aumercier M, Matthys P, Van Nieuwerburgh F, Kerre TCC, Taghon T, Van Vlierberghe P, Vandekerckhove B, Leclercq G. Taveirne S, et al. Among authors: van ammel e, van nieuwerburgh f, van loocke w, van vlierberghe p. Blood. 2020 Jul 16;136(3):288-298. doi: 10.1182/blood.2020005204. Blood. 2020. PMID: 32350509 Free article.
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia.
Roels J, Thénoz M, Szarzyńska B, Landfors M, De Coninck S, Demoen L, Provez L, Kuchmiy A, Strubbe S, Reunes L, Pieters T, Matthijssens F, Van Loocke W, Erarslan-Uysal B, Richter-Pechańska P, Declerck K, Lammens T, De Moerloose B, Deforce D, Van Nieuwerburgh F, Cheung LC, Kotecha RS, Mansour MR, Ghesquière B, Van Camp G, Berghe WV, Kowalczyk JR, Szczepański T, Davé UP, Kulozik AE, Goossens S, Curtis DJ, Taghon T, Dawidowska M, Degerman S, Van Vlierberghe P. Roels J, et al. Among authors: van nieuwerburgh f, van loocke w, van vlierberghe p, van camp g. Blood Cancer Discov. 2020 Nov;1(3):274-289. doi: 10.1158/2643-3230.BCD-20-0059. Epub 2020 Sep 23. Blood Cancer Discov. 2020. PMID: 33179015 Free PMC article.
T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells.
Kiekens L, Van Loocke W, Taveirne S, Wahlen S, Persyn E, Van Ammel E, De Vos Z, Matthys P, Van Nieuwerburgh F, Taghon T, Van Vlierberghe P, Vandekerckhove B, Leclercq G. Kiekens L, et al. Among authors: van ammel e, van nieuwerburgh f, van loocke w, van vlierberghe p. Front Immunol. 2021 Sep 24;12:732511. doi: 10.3389/fimmu.2021.732511. eCollection 2021. Front Immunol. 2021. PMID: 34630413 Free PMC article.
The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency.
Wahlen S, Matthijssens F, Van Loocke W, Taveirne S, Kiekens L, Persyn E, Van Ammel E, De Vos Z, De Munter S, Matthys P, Van Nieuwerburgh F, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Wahlen S, et al. Among authors: van ammel e, van nieuwerburgh f, van loocke w, van vlierberghe p. Elife. 2022 Jul 6;11:e80320. doi: 10.7554/eLife.80320. Elife. 2022. PMID: 35793229 Free PMC article.
Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development.
Roels J, Van Hulle J, Lavaert M, Kuchmiy A, Strubbe S, Putteman T, Vandekerckhove B, Leclercq G, Van Nieuwerburgh F, Boehme L, Taghon T. Roels J, et al. Among authors: van hulle j, van nieuwerburgh f. Front Immunol. 2022 Jul 28;13:960918. doi: 10.3389/fimmu.2022.960918. eCollection 2022. Front Immunol. 2022. PMID: 35967340 Free PMC article.
TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality.
Persyn E, Wahlen S, Kiekens L, Taveirne S, Van Loocke W, Van Ammel E, Van Nieuwerburgh F, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Persyn E, et al. Among authors: van ammel e, van nieuwerburgh f, van loocke w, van vlierberghe p. Int J Mol Sci. 2022 Sep 26;23(19):11345. doi: 10.3390/ijms231911345. Int J Mol Sci. 2022. PMID: 36232644 Free PMC article.
IRF2 is required for development and functional maturation of human NK cells.
Persyn E, Wahlen S, Kiekens L, Van Loocke W, Siwe H, Van Ammel E, De Vos Z, Van Nieuwerburgh F, Matthys P, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Persyn E, et al. Among authors: van ammel e, van nieuwerburgh f, van loocke w, van vlierberghe p. Front Immunol. 2022 Dec 5;13:1038821. doi: 10.3389/fimmu.2022.1038821. eCollection 2022. Front Immunol. 2022. PMID: 36544762 Free PMC article.
253 results