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Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
Wanior M, Preuss F, Ni X, Krämer A, Mathea S, Göbel T, Heidenreich D, Simonyi S, Kahnt AS, Joerger AC, Knapp S. Wanior M, et al. Among authors: mathea s. J Med Chem. 2020 Dec 10;63(23):14680-14699. doi: 10.1021/acs.jmedchem.0c01242. Epub 2020 Nov 20. J Med Chem. 2020. PMID: 33216538
Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib.
Mathea S, Abdul Azeez KR, Salah E, Tallant C, Wolfreys F, Konietzny R, Fischer R, Lou HJ, Brennan PE, Schnapp G, Pautsch A, Kessler BM, Turk BE, Knapp S. Mathea S, et al. ACS Chem Biol. 2016 Jun 17;11(6):1595-602. doi: 10.1021/acschembio.6b00043. Epub 2016 Mar 31. ACS Chem Biol. 2016. PMID: 26999302 Free PMC article.
Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.
Gebel J, Luh LM, Coutandin D, Osterburg C, Löhr F, Schäfer B, Frombach AS, Sumyk M, Buchner L, Krojer T, Salah E, Mathea S, Güntert P, Knapp S, Dötsch V. Gebel J, et al. Among authors: mathea s. Cell Death Differ. 2016 Dec;23(12):1930-1940. doi: 10.1038/cdd.2016.83. Epub 2016 Oct 7. Cell Death Differ. 2016. PMID: 27716744 Free PMC article.
Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1.
Suh JL, Watts B, Stuckey JI, Norris-Drouin JL, Cholensky SH, Dickson BM, An Y, Mathea S, Salah E, Knapp S, Khan A, Adams AT, Strahl BD, Sagum CA, Bedford MT, James LI, Kireev DB, Frye SV. Suh JL, et al. Among authors: mathea s. Biochemistry. 2018 Apr 10;57(14):2140-2149. doi: 10.1021/acs.biochem.8b00150. Epub 2018 Mar 28. Biochemistry. 2018. PMID: 29558110 Free PMC article.
A Pseudo-Kinase Double Act.
Preuß F, Mathea S, Knapp S. Preuß F, et al. Among authors: mathea s. Structure. 2018 Apr 3;26(4):527-528. doi: 10.1016/j.str.2018.03.008. Structure. 2018. PMID: 29617648 Free article.
A Pseudo-Kinase Double Act.
Preuß F, Mathea S, Knapp S. Preuß F, et al. Among authors: mathea s. Structure. 2018 Nov 6;26(11):1564. doi: 10.1016/j.str.2018.10.019. Structure. 2018. PMID: 30403994 Free article. No abstract available.
Lessons from LIMK1 enzymology and their impact on inhibitor design.
Salah E, Chatterjee D, Beltrami A, Tumber A, Preuss F, Canning P, Chaikuad A, Knaus P, Knapp S, Bullock AN, Mathea S. Salah E, et al. Among authors: mathea s. Biochem J. 2019 Nov 15;476(21):3197-3209. doi: 10.1042/BCJ20190517. Biochem J. 2019. PMID: 31652302 Free PMC article.
Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Sheetz JB, Mathea S, Karvonen H, Malhotra K, Chatterjee D, Niininen W, Perttilä R, Preuss F, Suresh K, Stayrook SE, Tsutsui Y, Radhakrishnan R, Ungureanu D, Knapp S, Lemmon MA. Sheetz JB, et al. Among authors: mathea s. Mol Cell. 2020 Aug 6;79(3):390-405.e7. doi: 10.1016/j.molcel.2020.06.018. Epub 2020 Jul 2. Mol Cell. 2020. PMID: 32619402 Free PMC article.
39 results