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Defective immunometabolism pathways in cystic fibrosis macrophages.
Hamilton K, Krause K, Badr A, Daily K, Estfanous S, Eltobgy M, Khweek AA, Anne MNK, Carafice C, Baetzhold D, Tonniges JR, Zhang X, Gavrilin MA, Parinandi NL, Amer AO. Hamilton K, et al. Among authors: amer ao. J Cyst Fibros. 2021 Jul;20(4):664-672. doi: 10.1016/j.jcf.2020.10.006. Epub 2020 Nov 15. J Cyst Fibros. 2021. PMID: 33208300 Free PMC article.
Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection.
Akhter A, Gavrilin MA, Frantz L, Washington S, Ditty C, Limoli D, Day C, Sarkar A, Newland C, Butchar J, Marsh CB, Wewers MD, Tridandapani S, Kanneganti TD, Amer AO. Akhter A, et al. Among authors: amer ao. PLoS Pathog. 2009 Apr;5(4):e1000361. doi: 10.1371/journal.ppat.1000361. Epub 2009 Apr 3. PLoS Pathog. 2009. PMID: 19343209 Free PMC article.
Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages.
Abdelaziz DH, Gavrilin MA, Akhter A, Caution K, Kotrange S, Khweek AA, Abdulrahman BA, Hassan ZA, El-Sharkawi FZ, Bedi SS, Ladner K, Gonzalez-Mejia ME, Doseff AI, Mostafa M, Kanneganti TD, Guttridge D, Marsh CB, Wewers MD, Amer AO. Abdelaziz DH, et al. Among authors: amer ao. Front Microbiol. 2011 Feb 14;2:18. doi: 10.3389/fmicb.2011.00018. eCollection 2011. Front Microbiol. 2011. PMID: 21713115 Free PMC article.
Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.
Abdulrahman BA, Khweek AA, Akhter A, Caution K, Kotrange S, Abdelaziz DH, Newland C, Rosales-Reyes R, Kopp B, McCoy K, Montione R, Schlesinger LS, Gavrilin MA, Wewers MD, Valvano MA, Amer AO. Abdulrahman BA, et al. Among authors: amer ao. Autophagy. 2011 Nov;7(11):1359-70. doi: 10.4161/auto.7.11.17660. Epub 2011 Nov 1. Autophagy. 2011. PMID: 21997369 Free PMC article.
Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia.
Gavrilin MA, Abdelaziz DH, Mostafa M, Abdulrahman BA, Grandhi J, Akhter A, Abu Khweek A, Aubert DF, Valvano MA, Wewers MD, Amer AO. Gavrilin MA, et al. Among authors: amer ao. J Immunol. 2012 Apr 1;188(7):3469-77. doi: 10.4049/jimmunol.1102272. Epub 2012 Feb 24. J Immunol. 2012. PMID: 22368275 Free PMC article.
Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.
Akhter A, Caution K, Abu Khweek A, Tazi M, Abdulrahman BA, Abdelaziz DH, Voss OH, Doseff AI, Hassan H, Azad AK, Schlesinger LS, Wewers MD, Gavrilin MA, Amer AO. Akhter A, et al. Among authors: amer ao. Immunity. 2012 Jul 27;37(1):35-47. doi: 10.1016/j.immuni.2012.05.001. Epub 2012 May 31. Immunity. 2012. PMID: 22658523 Free PMC article.
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