Decker AM - Search Results

1

Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists.

Rahman MT, Decker AM, Langston TL, Mathews KM, Laudermilk L, Maitra R, Ma W, Darcq E, Kieffer BL, Jin C. Rahman MT, et al. Among authors: decker am. J Med Chem. 2020 Dec 10;63(23):14989-15012. doi: 10.1021/acs.jmedchem.0c01581. Epub 2020 Nov 18. J Med Chem. 2020. PMID: 33205975 Free PMC article.

2

Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction.

Carroll FI, Blough BE, Abraham P, Mills AC, Holleman JA, Wolckenhauer SA, Decker AM, Landavazo A, McElroy KT, Navarro HA, Gatch MB, Forster MJ. Carroll FI, et al. Among authors: decker am. J Med Chem. 2009 Nov 12;52(21):6768-81. doi: 10.1021/jm901189z. J Med Chem. 2009. PMID: 19821577

3

Truncated Orexin Peptides: Structure-Activity Relationship Studies.

German NA, Decker AM, Gilmour BP, Thomas BF, Zhang Y. German NA, et al. Among authors: decker am. ACS Med Chem Lett. 2013 Dec 12;4(12):1224-1227. doi: 10.1021/ml400333a. ACS Med Chem Lett. 2013. PMID: 24707347 Free PMC article.

4

Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor.

Jin C, Decker AM, Huang XP, Gilmour BP, Blough BE, Roth BL, Hu Y, Gill JB, Zhang XP. Jin C, et al. Among authors: decker am. ACS Chem Neurosci. 2014 Jul 16;5(7):576-87. doi: 10.1021/cn500082p. Epub 2014 May 14. ACS Chem Neurosci. 2014. PMID: 24793972 Free PMC article.

5

Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1).

German N, Decker AM, Gilmour BP, Gay EA, Wiley JL, Thomas BF, Zhang Y. German N, et al. Among authors: decker am. J Med Chem. 2014 Sep 25;57(18):7758-69. doi: 10.1021/jm501042u. Epub 2014 Sep 4. J Med Chem. 2014. PMID: 25162172 Free PMC article.

6

Alpha-ethyltryptamines as dual dopamine-serotonin releasers.

Blough BE, Landavazo A, Partilla JS, Decker AM, Page KM, Baumann MH, Rothman RB. Blough BE, et al. Among authors: decker am. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4754-4758. doi: 10.1016/j.bmcl.2014.07.062. Epub 2014 Jul 29. Bioorg Med Chem Lett. 2014. PMID: 25193229 Free PMC article.

7

Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators.

Nguyen T, German N, Decker AM, Li JX, Wiley JL, Thomas BF, Kenakin TP, Zhang Y. Nguyen T, et al. Among authors: decker am. Bioorg Med Chem. 2015 May 1;23(9):2195-2203. doi: 10.1016/j.bmc.2015.02.058. Epub 2015 Mar 7. Bioorg Med Chem. 2015. PMID: 25797163 Free PMC article.

8

The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.

Perrey DA, Decker AM, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Perrey DA, et al. Among authors: decker am. Bioorg Med Chem. 2015 Sep 1;23(17):5709-24. doi: 10.1016/j.bmc.2015.07.013. Epub 2015 Jul 16. Bioorg Med Chem. 2015. PMID: 26216017 Free PMC article.

9

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3- and 4-methyl substituents.

Carroll FI, Gichinga MG, Kormos CM, Maitra R, Runyon SP, Thomas JB, Mascarella SW, Decker AM, Navarro HA. Carroll FI, et al. Among authors: decker am. Bioorg Med Chem. 2015 Oct 1;23(19):6379-88. doi: 10.1016/j.bmc.2015.08.025. Epub 2015 Aug 25. Bioorg Med Chem. 2015. PMID: 26342544 Free PMC article.

10

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteres.

Kormos CM, Gichinga MG, Runyon SP, Thomas JB, Mascarella SW, Decker AM, Navarro HA, Carroll FI. Kormos CM, et al. Among authors: decker am. Bioorg Med Chem. 2016 Aug 15;24(16):3842-8. doi: 10.1016/j.bmc.2016.06.029. Epub 2016 Jun 15. Bioorg Med Chem. 2016. PMID: 27364611 Free PMC article.

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