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High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents.
Kanjanasirirat P, Suksatu A, Manopwisedjaroen S, Munyoo B, Tuchinda P, Jearawuttanakul K, Seemakhan S, Charoensutthivarakul S, Wongtrakoongate P, Rangkasenee N, Pitiporn S, Waranuch N, Chabang N, Khemawoot P, Sa-Ngiamsuntorn K, Pewkliang Y, Thongsri P, Chutipongtanate S, Hongeng S, Borwornpinyo S, Thitithanyanont A. Kanjanasirirat P, et al. Among authors: charoensutthivarakul s. Sci Rep. 2020 Nov 17;10(1):19963. doi: 10.1038/s41598-020-77003-3. Sci Rep. 2020. PMID: 33203926 Free PMC article.
Anti-SARS-CoV-2 Activity of Andrographis paniculata Extract and Its Major Component Andrographolide in Human Lung Epithelial Cells and Cytotoxicity Evaluation in Major Organ Cell Representatives.
Sa-Ngiamsuntorn K, Suksatu A, Pewkliang Y, Thongsri P, Kanjanasirirat P, Manopwisedjaroen S, Charoensutthivarakul S, Wongtrakoongate P, Pitiporn S, Chaopreecha J, Kongsomros S, Jearawuttanakul K, Wannalo W, Khemawoot P, Chutipongtanate S, Borwornpinyo S, Thitithanyanont A, Hongeng S. Sa-Ngiamsuntorn K, et al. Among authors: charoensutthivarakul s. J Nat Prod. 2021 Apr 23;84(4):1261-1270. doi: 10.1021/acs.jnatprod.0c01324. Epub 2021 Apr 12. J Nat Prod. 2021. PMID: 33844528
ECDD-S16 targets vacuolar ATPase: A potential inhibitor compound for pyroptosis-induced inflammation.
Ekchariyawat P, Saengfak R, Sanongkiet S, Charoenwongpaiboon T, Khongpraphan S, Mala S, Luangjindarat C, Munyoo B, Chabang N, Charoensutthivarakul S, Borwornpinyo S, Tuchinda P, Ponpuak M, Pudla M, Utaisincharoen P. Ekchariyawat P, et al. Among authors: charoensutthivarakul s. PLoS One. 2023 Nov 27;18(11):e0292340. doi: 10.1371/journal.pone.0292340. eCollection 2023. PLoS One. 2023. PMID: 38011122 Free PMC article.
Frontiers in antibiotic alternatives for Clostridioides difficile infection.
Phanchana M, Harnvoravongchai P, Wongkuna S, Phetruen T, Phothichaisri W, Panturat S, Pipatthana M, Charoensutthivarakul S, Chankhamhaengdecha S, Janvilisri T. Phanchana M, et al. Among authors: charoensutthivarakul s. World J Gastroenterol. 2021 Nov 14;27(42):7210-7232. doi: 10.3748/wjg.v27.i42.7210. World J Gastroenterol. 2021. PMID: 34876784 Free PMC article.
Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach.
Charoensutthivarakul S, Thomas SE, Curran A, Brown KP, Belardinelli JM, Whitehouse AJ, Acebrón-García-de-Eulate M, Sangan J, Gramani SG, Jackson M, Mendes V, Floto RA, Blundell TL, Coyne AG, Abell C. Charoensutthivarakul S, et al. ACS Infect Dis. 2022 Feb 11;8(2):296-309. doi: 10.1021/acsinfecdis.1c00432. Epub 2022 Jan 17. ACS Infect Dis. 2022. PMID: 35037462 Free PMC article.
Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7.
Ismail HM, Barton V, Phanchana M, Charoensutthivarakul S, Wong MH, Hemingway J, Biagini GA, O'Neill PM, Ward SA. Ismail HM, et al. Among authors: charoensutthivarakul s. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2080-5. doi: 10.1073/pnas.1600459113. Epub 2016 Feb 8. Proc Natl Acad Sci U S A. 2016. PMID: 26858419 Free PMC article.
Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping.
Thomas SE, Collins P, James RH, Mendes V, Charoensutthivarakul S, Radoux C, Abell C, Coyne AG, Floto RA, von Delft F, Blundell TL. Thomas SE, et al. Among authors: charoensutthivarakul s. Philos Trans A Math Phys Eng Sci. 2019 Jun 17;377(2147):20180422. doi: 10.1098/rsta.2018.0422. Philos Trans A Math Phys Eng Sci. 2019. PMID: 31030650 Free PMC article.
A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen).
Frederickson M, Selvam IR, Evangelopoulos D, McLean KJ, Katariya MM, Tunnicliffe RB, Campbell B, Kavanagh ME, Charoensutthivarakul S, Blankley RT, Levy CW, de Carvalho LPS, Leys D, Munro AW, Coyne AG, Abell C. Frederickson M, et al. Among authors: charoensutthivarakul s. Eur J Med Chem. 2022 Feb 15;230:114105. doi: 10.1016/j.ejmech.2022.114105. Epub 2022 Jan 11. Eur J Med Chem. 2022. PMID: 35065413 Free PMC article.
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
Pidathala C, Amewu R, Pacorel B, Nixon GL, Gibbons P, Hong WD, Leung SC, Berry NG, Sharma R, Stocks PA, Srivastava A, Shone AE, Charoensutthivarakul S, Taylor L, Berger O, Mbekeani A, Hill A, Fisher NE, Warman AJ, Biagini GA, Ward SA, O'Neill PM. Pidathala C, et al. Among authors: charoensutthivarakul s. J Med Chem. 2012 Mar 8;55(5):1831-43. doi: 10.1021/jm201179h. Epub 2012 Feb 24. J Med Chem. 2012. PMID: 22364416 Free PMC article.
18 results