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Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth.
Geeraerts SL, Kampen KR, Rinaldi G, Gupta P, Planque M, Louros N, Heylen E, De Cremer K, De Brucker K, Vereecke S, Verbelen B, Vermeersch P, Schymkowitz J, Rousseau F, Cassiman D, Fendt SM, Voet A, Cammue BPA, Thevissen K, De Keersmaecker K. Geeraerts SL, et al. Among authors: verbelen b. Mol Cancer Ther. 2021 Jan;20(1):50-63. doi: 10.1158/1535-7163.MCT-20-0480. Epub 2020 Nov 17. Mol Cancer Ther. 2021. PMID: 33203732 Free PMC article.
The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Kampen KR, Sulima SO, Verbelen B, Girardi T, Vereecke S, Rinaldi G, Verbeeck J, Op de Beeck J, Uyttebroeck A, Meijerink JPP, Moorman AV, Harrison CJ, Spincemaille P, Cools J, Cassiman D, Fendt SM, Vermeersch P, De Keersmaecker K. Kampen KR, et al. Among authors: verbelen b. Leukemia. 2019 Feb;33(2):319-332. doi: 10.1038/s41375-018-0176-z. Epub 2018 Jun 21. Leukemia. 2019. PMID: 29930300 Free PMC article.
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Kampen KR, Fancello L, Girardi T, Rinaldi G, Planque M, Sulima SO, Loayza-Puch F, Verbelen B, Vereecke S, Verbeeck J, Op de Beeck J, Royaert J, Vermeersch P, Cassiman D, Cools J, Agami R, Fiers M, Fendt SM, De Keersmaecker K. Kampen KR, et al. Among authors: verbelen b. Nat Commun. 2019 Jun 11;10(1):2542. doi: 10.1038/s41467-019-10508-2. Nat Commun. 2019. PMID: 31186416 Free PMC article.
Correction: The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Kampen KR, Sulima SO, Verbelen B, Girardi T, Vereecke S, Fancello L, Rinaldi G, Verbeeck J, Op de Beeck J, Uyttebroeck A, Meijerink JPP, Moorman AV, Harrison CJ, Spincemaille P, Cools J, Cassiman D, Fendt SM, Vermeersch P, De Keersmaecker K. Kampen KR, et al. Among authors: verbelen b. Leukemia. 2019 Apr;33(4):1055-1062. doi: 10.1038/s41375-019-0424-x. Leukemia. 2019. PMID: 30850735 Free PMC article.
Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells.
Verbelen B, Girardi T, Sulima SO, Vereecke S, Verstraete P, Verbeeck J, Royaert J, Cinque S, Montanaro L, Penzo M, Imbrechts M, Geukens N, Geuens T, Dierckx K, Pepe D, Kampen K, De Keersmaecker K. Verbelen B, et al. Eng Life Sci. 2022 Jan 14;22(2):100-114. doi: 10.1002/elsc.202100124. eCollection 2022 Feb. Eng Life Sci. 2022. PMID: 35140557 Free PMC article.
Impact of the Keto-Enol Tautomeric Equilibrium on the BODIPY Chromophore.
Leen V, Laine M, Ngongo JM, Lipkowski P, Verbelen B, Kochel A, Dehaen W, Van der Auweraer M, Nadtochenko V, Filarowski A. Leen V, et al. Among authors: verbelen b. J Phys Chem A. 2018 Jul 19;122(28):5955-5961. doi: 10.1021/acs.jpca.8b03489. Epub 2018 Jul 3. J Phys Chem A. 2018. PMID: 29939739
15 results