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Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.
Ibrahim TS, Hawwas MM, Taher ES, Alhakamy NA, Alfaleh MA, Elagawany M, Elgendy B, Zayed GM, Mohamed MFA, Abdel-Samii ZK, Elshaier YAMM. Ibrahim TS, et al. Among authors: abdel samii zk. Bioorg Chem. 2020 Dec;105:104352. doi: 10.1016/j.bioorg.2020.104352. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33080494
Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM. Ibrahim TS, et al. Among authors: abdel samii zk. J Enzyme Inhib Med Chem. 2021 Dec;36(1):802-818. doi: 10.1080/14756366.2021.1899168. J Enzyme Inhib Med Chem. 2021. PMID: 33730937 Free PMC article.
New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2.
Seliem IA, Panda SS, Girgis AS, Moatasim Y, Kandeil A, Mostafa A, Ali MA, Nossier ES, Rasslan F, Srour AM, Sakhuja R, Ibrahim TS, Abdel-Samii ZKM, Al-Mahmoudy AMM. Seliem IA, et al. Among authors: abdel samii zkm. Bioorg Chem. 2021 Sep;114:105117. doi: 10.1016/j.bioorg.2021.105117. Epub 2021 Jun 23. Bioorg Chem. 2021. PMID: 34214752 Free PMC article.
Development of Isatin-Based Schiff Bases Targeting VEGFR-2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies.
Seliem IA, Panda SS, Girgis AS, Tran QL, Said MF, Bekheit MS, Abdelnaser A, Nasr S, Fayad W, Soliman AAF, Sakhuja R, Ibrahim TS, Abdel-Samii ZKM, Al-Mahmoudy AMM. Seliem IA, et al. Among authors: abdel samii zkm. ChemMedChem. 2022 Jul 5;17(13):e202200164. doi: 10.1002/cmdc.202200164. Epub 2022 Jun 1. ChemMedChem. 2022. PMID: 35511203
Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening.
Agha KA, Abo-Dya NE, Issahaku AR, Agoni C, Soliman MES, Abdel-Aal EH, Abdel-Samii ZK, Ibrahim TS. Agha KA, et al. Among authors: abdel samii zk. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1241-1256. doi: 10.1080/14756366.2022.2068147. J Enzyme Inhib Med Chem. 2022. PMID: 35484855 Free PMC article.
22 results