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Pharmacological Modulators of Tau Aggregation and Spreading.
Dominguez-Meijide A, Vasili E, Outeiro TF. Dominguez-Meijide A, et al. Among authors: outeiro tf. Brain Sci. 2020 Nov 13;10(11):858. doi: 10.3390/brainsci10110858. Brain Sci. 2020. PMID: 33203009 Free PMC article. Review.
Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding.
Chiang AN, Liang M, Dominguez-Meijide A, Masaracchia C, Goeckeler-Fried JL, Mazzone CS, Newhouse DW, Kendsersky NM, Yates ME, Manos-Turvey A, Needham PG, Outeiro TF, Wipf P, Brodsky JL. Chiang AN, et al. Among authors: outeiro tf. Bioorg Med Chem. 2019 Jan 1;27(1):79-91. doi: 10.1016/j.bmc.2018.11.011. Epub 2018 Nov 15. Bioorg Med Chem. 2019. PMID: 30528127 Free PMC article.
Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies.
Szegő ÉM, Dominguez-Meijide A, Gerhardt E, König A, Koss DJ, Li W, Pinho R, Fahlbusch C, Johnson M, Santos P, Villar-Piqué A, Thom T, Rizzoli S, Schmitz M, Li J, Zerr I, Attems J, Jahn O, Outeiro TF. Szegő ÉM, et al. Among authors: outeiro tf. Cell Rep. 2019 Jul 2;28(1):65-77.e6. doi: 10.1016/j.celrep.2019.06.009. Cell Rep. 2019. PMID: 31269451 Free article.
Synucleinopathies: Where we are and where we need to go.
Brás IC, Dominguez-Meijide A, Gerhardt E, Koss D, Lázaro DF, Santos PI, Vasili E, Xylaki M, Outeiro TF. Brás IC, et al. Among authors: outeiro tf. J Neurochem. 2020 May;153(4):433-454. doi: 10.1111/jnc.14965. Epub 2020 Feb 19. J Neurochem. 2020. PMID: 31957016 Free article. Review.
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo.
Dominguez-Meijide A, Parrales V, Vasili E, González-Lizárraga F, König A, Lázaro DF, Lannuzel A, Haik S, Del Bel E, Chehín R, Raisman-Vozari R, Michel PP, Bizat N, Outeiro TF. Dominguez-Meijide A, et al. Among authors: outeiro tf. Neurobiol Dis. 2021 Apr;151:105256. doi: 10.1016/j.nbd.2021.105256. Epub 2021 Jan 8. Neurobiol Dis. 2021. PMID: 33429042 Free article.
Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity.
Medina L, González-Lizárraga F, Dominguez-Meijide A, Ploper D, Parrales V, Sequeira S, Cima-Omori MS, Zweckstetter M, Del Bel E, Michel PP, Outeiro TF, Raisman-Vozari R, Chehín R, Socias SB. Medina L, et al. Among authors: outeiro tf. Front Aging Neurosci. 2021 Mar 22;13:635760. doi: 10.3389/fnagi.2021.635760. eCollection 2021. Front Aging Neurosci. 2021. PMID: 33828477 Free PMC article.
329 results