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Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor.
Barros TG, Santos JAN, de Souza BEG, Sodero ACR, de Souza AMT, da Silva DP, Rodrigues CR, Pinheiro S, Dias LRS, Abrahim-Vieira B, Puzer L, Muri EMF. Barros TG, et al. Among authors: muri emf. Bioorg Med Chem Lett. 2017 Jan 15;27(2):314-318. doi: 10.1016/j.bmcl.2016.11.051. Epub 2016 Nov 18. Bioorg Med Chem Lett. 2017. PMID: 27914800
Synthesis and mechanistic evaluation of novel N'-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents.
Lourenço AL, Salvador RRS, Silva LA, Saito MS, Mello JFR, Cabral LM, Rodrigues CR, Vera MAF, Muri EMF, de Souza AMT, Craik CS, Dias LRS, Castro HC, Sathler PC. Lourenço AL, et al. Among authors: muri emf. Eur J Med Chem. 2017 Jul 28;135:213-229. doi: 10.1016/j.ejmech.2017.04.023. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28453995
3-Acyltetramic acids as a novel class of inhibitors for human kallikreins 5 and 7.
de Souza AS, Pacheco BDC, Pinheiro S, Muri EMF, Dias LRS, Lima CHS, Garrett R, de Moraes MBM, de Souza BEG, Puzer L. de Souza AS, et al. Among authors: muri emf. Bioorg Med Chem Lett. 2019 May 1;29(9):1094-1098. doi: 10.1016/j.bmcl.2019.02.031. Epub 2019 Feb 27. Bioorg Med Chem Lett. 2019. PMID: 30833107
Isosorbide-based peptidomimetics as inhibitors of hepatitis C virus serine protease.
Portela AC, Barros TG, Lima CHDS, Dias LRS, Azevedo PHRA, Dantas ASCL, Mohana-Borges R, Ventura GT, Pinheiro S, Muri EMF. Portela AC, et al. Among authors: muri emf. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3661-3665. doi: 10.1016/j.bmcl.2017.07.027. Epub 2017 Jul 8. Bioorg Med Chem Lett. 2017. PMID: 28729054
Isomannide derivatives as new class of inhibitors for human kallikrein 7.
Freitas RF, Teixeira TS, Barros TG, Santos JA, Kondo MY, Juliano MA, Juliano L, Blaber M, Antunes OA, Abrahão O Jr, Pinheiro S, Muri EM, Puzer L. Freitas RF, et al. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6072-5. doi: 10.1016/j.bmcl.2012.08.047. Epub 2012 Aug 21. Bioorg Med Chem Lett. 2012. PMID: 22959247
19 results