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APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response.
Conner KL, Shaik AN, Marshall KA, Floyd AM, Ekinci E, Lindquist J, Sawant A, Lei W, Adolph MB, Chelico L, Siriwardena SU, Bhagwat A, Kim S, Cote ML, Patrick SM. Conner KL, et al. Among authors: sawant a. NAR Cancer. 2020 Dec;2(4):zcaa033. doi: 10.1093/narcan/zcaa033. Epub 2020 Nov 6. NAR Cancer. 2020. PMID: 33196045 Free PMC article.
Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration.
Huo Y, Sawant A, Tan Y, Mahdi AH, Li T, Ma H, Bhatt V, Yan R, Coleman J, Dreyfus CF, Guo JY, Mouradian MM, White E, Xia B. Huo Y, et al. Among authors: sawant a. PLoS Genet. 2022 Apr 11;18(4):e1010138. doi: 10.1371/journal.pgen.1010138. eCollection 2022 Apr. PLoS Genet. 2022. PMID: 35404932 Free PMC article.
Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival.
Yang Y, Gomez M, Marsh T, Poillet-Perez L, Sawant A, Chen L, Park NR, Jackson SR, Hu Z, Alon N, Liu C, Debnath J, Guan JL, Davidson S, Verzi M, White E. Yang Y, et al. Among authors: sawant a. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2202016119. doi: 10.1073/pnas.2202016119. Epub 2022 May 10. Proc Natl Acad Sci U S A. 2022. PMID: 35537042 Free PMC article.
Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer.
Cararo Lopes E, Sawant A, Moore D, Ke H, Shi F, Laddha S, Chen Y, Sharma A, Naumann J, Guo JY, Gomez M, Ibrahim M, Smith TL, Riedlinger GM, Lattime EC, Trooskin S, Ganesan S, Su X, Pasqualini R, Arap W, De S, Chan CS, White E. Cararo Lopes E, et al. Among authors: sawant a. Clin Transl Med. 2023 Jun;13(6):e1298. doi: 10.1002/ctm2.1298. Clin Transl Med. 2023. PMID: 37317665 Free PMC article.
370 results