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An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody-Drug Conjugates.
Merkul E, Muns JA, Sijbrandi NJ, Houthoff HJ, Nijmeijer B, van Rheenen G, Reedijk J, van Dongen GAMS. Merkul E, et al. Among authors: van rheenen g, van dongen gams. Angew Chem Int Ed Engl. 2021 Feb 8;60(6):3008-3015. doi: 10.1002/anie.202011593. Epub 2021 Jan 15. Angew Chem Int Ed Engl. 2021. PMID: 33185916 Free PMC article.
In Vivo Characterization of Platinum(II)-Based Linker Technology for the Development of Antibody-Drug Conjugates: Taking Advantage of Dual Labeling with 195mPt and 89Zr.
Muns JA, Montserrat V, Houthoff HJ, Codée-van der Schilden K, Zwaagstra O, Sijbrandi NJ, Merkul E, van Dongen GAMS. Muns JA, et al. Among authors: van dongen gams. J Nucl Med. 2018 Jul;59(7):1146-1151. doi: 10.2967/jnumed.117.206672. Epub 2018 Mar 1. J Nucl Med. 2018. PMID: 29496986 Free article.
The tumor targeting performance of anti-CD166 Probody drug conjugate CX-2009 and its parental derivatives as monitored by 89Zr-immuno-PET in xenograft bearing mice.
Chomet M, Schreurs M, Nguyen M, Howng B, Villanueva R, Krimm M, Vasiljeva O, van Dongen GAMS, Vugts DJ. Chomet M, et al. Among authors: van dongen gams. Theranostics. 2020 Apr 27;10(13):5815-5828. doi: 10.7150/thno.44334. eCollection 2020. Theranostics. 2020. PMID: 32483421 Free PMC article.
Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinical 89Zr-immuno-PET.
Chomet M, Schreurs M, Bolijn MJ, Verlaan M, Beaino W, Brown K, Poot AJ, Windhorst AD, Gill H, Marik J, Williams S, Cowell J, Gasser G, Mindt TL, van Dongen GAMS, Vugts DJ. Chomet M, et al. Among authors: van dongen gams. Eur J Nucl Med Mol Imaging. 2021 Mar;48(3):694-707. doi: 10.1007/s00259-020-05002-7. Epub 2020 Sep 5. Eur J Nucl Med Mol Imaging. 2021. PMID: 32889615 Free PMC article.
237 results