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Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility.
Wang Y, Shi Q, Li M, Zhao M, Reddy Gopireddy R, Teoh JP, Xu B, Zhu C, Ireton KE, Srinivasan S, Chen S, Gasser PJ, Bossuyt J, Hell JW, Bers DM, Xiang YK. Wang Y, et al. Among authors: hell jw. Circ Res. 2021 Jan 22;128(2):246-261. doi: 10.1161/CIRCRESAHA.120.317452. Epub 2020 Nov 13. Circ Res. 2021. PMID: 33183171 Free PMC article.
Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor.
Patriarchi T, Qian H, Di Biase V, Malik ZA, Chowdhury D, Price JL, Hammes EA, Buonarati OR, Westenbroek RE, Catterall WA, Hofmann F, Xiang YK, Murphy GG, Chen CY, Navedo MF, Hell JW. Patriarchi T, et al. Among authors: hell jw. EMBO J. 2016 Jun 15;35(12):1330-45. doi: 10.15252/embj.201593409. Epub 2016 Apr 21. EMBO J. 2016. PMID: 27103070 Free PMC article.
Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons.
Qian H, Patriarchi T, Price JL, Matt L, Lee B, Nieves-Cintrón M, Buonarati OR, Chowdhury D, Nanou E, Nystoriak MA, Catterall WA, Poomvanicha M, Hofmann F, Navedo MF, Hell JW. Qian H, et al. Among authors: hell jw. Sci Signal. 2017 Jan 24;10(463):eaaf9659. doi: 10.1126/scisignal.aaf9659. Sci Signal. 2017. PMID: 28119465 Free PMC article.
165 results