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LRRK2 mediates tubulation and vesicle sorting from lysosomes.
Bonet-Ponce L, Beilina A, Williamson CD, Lindberg E, Kluss JH, Saez-Atienzar S, Landeck N, Kumaran R, Mamais A, Bleck CKE, Li Y, Cookson MR. Bonet-Ponce L, et al. Among authors: li y. Sci Adv. 2020 Nov 11;6(46):eabb2454. doi: 10.1126/sciadv.abb2454. Print 2020 Nov. Sci Adv. 2020. PMID: 33177079 Free PMC article.
Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways.
Reyniers L, Del Giudice MG, Civiero L, Belluzzi E, Lobbestael E, Beilina A, Arrigoni G, Derua R, Waelkens E, Li Y, Crosio C, Iaccarino C, Cookson MR, Baekelandt V, Greggio E, Taymans JM. Reyniers L, et al. Among authors: li y. J Neurochem. 2014 Oct;131(2):239-50. doi: 10.1111/jnc.12798. Epub 2014 Jul 14. J Neurochem. 2014. PMID: 24947832 Free PMC article.
Hexokinases link DJ-1 to the PINK1/parkin pathway.
Hauser DN, Mamais A, Conti MM, Primiani CT, Kumaran R, Dillman AA, Langston RG, Beilina A, Garcia JH, Diaz-Ruiz A, Bernier M, Fiesel FC, Hou X, Springer W, Li Y, de Cabo R, Cookson MR. Hauser DN, et al. Among authors: li y. Mol Neurodegener. 2017 Sep 29;12(1):70. doi: 10.1186/s13024-017-0212-x. Mol Neurodegener. 2017. PMID: 28962651 Free PMC article.
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis.
Heaton GR, Landeck N, Mamais A, Nalls MA, Nixon-Abell J, Kumaran R, Beilina A, Pellegrini L, Li Y; International Parkinson Disease Genomics Consortium (IPDGC); Harvey K, Cookson MR. Heaton GR, et al. Among authors: li y. Neurobiol Dis. 2020 Jul;141:104948. doi: 10.1016/j.nbd.2020.104948. Epub 2020 May 17. Neurobiol Dis. 2020. PMID: 32434048 Free PMC article.
LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies.
Kim C, Beilina A, Smith N, Li Y, Kim M, Kumaran R, Kaganovich A, Mamais A, Adame A, Iba M, Kwon S, Lee WJ, Shin SJ, Rissman RA, You S, Lee SJ, Singleton AB, Cookson MR, Masliah E. Kim C, et al. Among authors: li y. Sci Transl Med. 2020 Oct 14;12(565):eaay0399. doi: 10.1126/scitranslmed.aay0399. Sci Transl Med. 2020. PMID: 33055242 Free PMC article.
220,261 results
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