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Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance.
Calvo T, Reina-Ortiz C, Giraldos D, Gascón M, Woods D, Asenjo J, Marco-Brualla J, Azaceta G, Izquierdo I, Palomera L, Sánchez-Martínez D, Marzo I, Naval J, Vilches C, Villalba M, Anel A. Calvo T, et al. Sci Rep. 2020 Nov 10;10(1):19398. doi: 10.1038/s41598-020-76051-z. Sci Rep. 2020. PMID: 33173077 Free PMC article.
All-trans retinoic acid (ATRA) induces miR-23a expression, decreases CTSC expression and granzyme B activity leading to impaired NK cell cytotoxicity.
Sanchez-Martínez D, Krzywinska E, Rathore MG, Saumet A, Cornillon A, Lopez-Royuela N, Martínez-Lostao L, Ramirez-Labrada A, Lu ZY, Rossi JF, Fernández-Orth D, Escorza S, Anel A, Lecellier CH, Pardo J, Villalba M. Sanchez-Martínez D, et al. Int J Biochem Cell Biol. 2014 Apr;49:42-52. doi: 10.1016/j.biocel.2014.01.003. Epub 2014 Jan 15. Int J Biochem Cell Biol. 2014. PMID: 24440757
Human NK cells activated by EBV+ lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.
Sánchez-Martínez D, Azaceta G, Muntasell A, Aguiló N, Núñez D, Gálvez EM, Naval J, Anel A, Palomera L, Vilches C, Marzo I, Villalba M, Pardo J. Sánchez-Martínez D, et al. Oncoimmunology. 2015 Jan 9;4(3):e991613. doi: 10.4161/2162402X.2014.991613. eCollection 2015 Mar. Oncoimmunology. 2015. PMID: 25949911 Free PMC article.
Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors.
Sanchez-Martinez D, Allende-Vega N, Orecchioni S, Talarico G, Cornillon A, Vo DN, Rene C, Lu ZY, Krzywinska E, Anel A, Galvez EM, Pardo J, Robert B, Martineau P, Hicheri Y, Bertolini F, Cartron G, Villalba M. Sanchez-Martinez D, et al. Theranostics. 2018 Jun 14;8(14):3856-3869. doi: 10.7150/thno.25149. eCollection 2018. Theranostics. 2018. PMID: 30083264 Free PMC article.
Efficient preclinical treatment of cortical T cell acute lymphoblastic leukemia with T lymphocytes secreting anti-CD1a T cell engagers.
Jiménez-Reinoso A, Tirado N, Martinez-Moreno A, Díaz VM, García-Peydró M, Hangiu O, Díez-Alonso L, Albitre Á, Penela P, Toribio ML, Menéndez P, Álvarez-Vallina L, Sánchez Martínez D. Jiménez-Reinoso A, et al. Among authors: sanchez martinez d. J Immunother Cancer. 2022 Dec;10(12):e005333. doi: 10.1136/jitc-2022-005333. J Immunother Cancer. 2022. PMID: 36564128 Free PMC article.
Mouse granzyme K has pro-inflammatory potential.
Joeckel LT, Wallich R, Martin P, Sanchez-Martinez D, Weber FC, Martin SF, Borner C, Pardo J, Froelich C, Simon MM. Joeckel LT, et al. Cell Death Differ. 2011 Jul;18(7):1112-9. doi: 10.1038/cdd.2011.5. Epub 2011 Feb 11. Cell Death Differ. 2011. PMID: 21311565 Free PMC article.
Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia.
Sánchez-Martínez D, Baroni ML, Gutierrez-Agüera F, Roca-Ho H, Blanch-Lombarte O, González-García S, Torrebadell M, Junca J, Ramírez-Orellana M, Velasco-Hernández T, Bueno C, Fuster JL, Prado JG, Calvo J, Uzan B, Cools J, Camos M, Pflumio F, Toribio ML, Menéndez P. Sánchez-Martínez D, et al. Blood. 2019 May 23;133(21):2291-2304. doi: 10.1182/blood-2018-10-882944. Epub 2019 Feb 22. Blood. 2019. PMID: 30796021 Free PMC article.
41 results