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High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive patients.
Yeregui E, Viladés C, Domingo P, Ceausu A, Pacheco YM, Veloso S, Inciarte A, Vidal-González J, Peraire M, Perpiñán C, Falcó V, Masip J, Alba V, Vargas M, Martí A, Reverté L, Mallolas J, Vidal F, Peraire J, Rull A. Yeregui E, et al. Among authors: pacheco ym. EBioMedicine. 2020 Dec;62:103077. doi: 10.1016/j.ebiom.2020.103077. Epub 2020 Nov 6. EBioMedicine. 2020. PMID: 33166788 Free PMC article.
Evaluation of the pharmacogenetics of immune recovery in treated HIV-infected patients.
Peraire J, Viladés C, Pacheco YM, López-Dupla M, Domingo P, Gutiérrez M, Rosado I, Leal M, Richart C, Vidal F. Peraire J, et al. Among authors: pacheco ym. Expert Opin Drug Metab Toxicol. 2014 Jan;10(1):81-101. doi: 10.1517/17425255.2014.854330. Epub 2013 Nov 21. Expert Opin Drug Metab Toxicol. 2014. PMID: 24256435 Review.
Higher levels of IL-6, CD4 turnover and Treg frequency are already present before cART in HIV-infected subjects with later low CD4 recovery.
Rosado-Sánchez I, Jarrín I, Pozo-Balado MM, de Pablo-Bernal RS, Herrero-Fernández I, Alvarez-Ríos AI, Rodríguez-Gallego E, Genebat M, Vera M, Berenguer J, Martín ML, Bernal E, Vidal F, Blanco J, Leal M, Pacheco YM. Rosado-Sánchez I, et al. Among authors: pacheco ym. Antiviral Res. 2017 Jun;142:76-82. doi: 10.1016/j.antiviral.2017.03.015. Epub 2017 Mar 24. Antiviral Res. 2017. PMID: 28343846
A Lower Baseline CD4/CD8 T-Cell Ratio Is Independently Associated with Immunodiscordant Response to Antiretroviral Therapy in HIV-Infected Subjects.
Rosado-Sánchez I, Herrero-Fernández I, Álvarez-Ríos AI, Genebat M, Abad-Carrillo MA, Ruiz-Mateos E, Pulido F, González-García J, Montero M, Bernal-Morell E, Vidal F, Leal M, Pacheco YM. Rosado-Sánchez I, et al. Among authors: pacheco ym. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00605-17. doi: 10.1128/AAC.00605-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28559274 Free PMC article.
A baseline metabolomic signature is associated with immunological CD4+ T-cell recovery after 36 months of antiretroviral therapy in HIV-infected patients.
Rodríguez-Gallego E, Gómez J, Pacheco YM, Peraire J, Viladés C, Beltrán-Debón R, Mallol R, López-Dupla M, Veloso S, Alba V, Blanco J, Cañellas N, Rull A, Leal M, Correig X, Domingo P, Vidal F. Rodríguez-Gallego E, et al. Among authors: pacheco ym. AIDS. 2018 Mar 13;32(5):565-573. doi: 10.1097/QAD.0000000000001730. AIDS. 2018. PMID: 29280761 Free PMC article.
Circulating metabolomic profile can predict dyslipidemia in HIV patients undergoing antiretroviral therapy.
Rodríguez-Gallego E, Gómez J, Domingo P, Ferrando-Martínez S, Peraire J, Viladés C, Veloso S, López-Dupla M, Beltrán-Debón R, Alba V, Vargas M, Castellano AJ, Leal M, Pacheco YM, Ruiz-Mateos E, Gutiérrez F, Vidal F, Rull A; CORIS-NADES events Study Group. Rodríguez-Gallego E, et al. Among authors: pacheco ym. Atherosclerosis. 2018 Jun;273:28-36. doi: 10.1016/j.atherosclerosis.2018.04.008. Epub 2018 Apr 9. Atherosclerosis. 2018. PMID: 29677628 Free article.
HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation.
Rosado-Sánchez I, Herrero-Fernández I, Genebat M, Del Romero J, Riera M, Podzamczer D, Olalla J, Vidal F, Muñoz-Fernández MA, Leal M, Pacheco YM. Rosado-Sánchez I, et al. Among authors: pacheco ym. Front Immunol. 2018 Jul 18;9:1673. doi: 10.3389/fimmu.2018.01673. eCollection 2018. Front Immunol. 2018. PMID: 30073002 Free PMC article.
Genetic variation in CCR2 and CXCL12 genes impacts on CD4 restoration in patients initiating cART with advanced immunesupression.
Restrepo C, Gutierrez-Rivas M, Pacheco YM, García M, Blanco J, Medrano LM, Navarrete-Muñoz MA, Gutiérrez F, Miralles P, Dalmau D, Gómez JL, Górgolas M, Cabello A, Resino S, Benito JM, Rallón N; CoRIS and the HIV Biobank integrated in the Spanish AIDS Research Network Project RIS/EPICLIN 10_2015. Restrepo C, et al. Among authors: pacheco ym. PLoS One. 2019 Mar 28;14(3):e0214421. doi: 10.1371/journal.pone.0214421. eCollection 2019. PLoS One. 2019. PMID: 30921390 Free PMC article.
Glutaminolysis and lipoproteins are key factors in late immune recovery in successfully treated HIV-infected patients.
Rosado-Sánchez I, Rodríguez-Gallego E, Peraire J, Viladés C, Herrero P, Fanjul F, Gutiérrez F, Bernal E, Pelazas R, Leal M, Veloso S, López-Dupla M, Blanco J, Vidal F, Pacheco YM, Rull A. Rosado-Sánchez I, et al. Among authors: pacheco ym. Clin Sci (Lond). 2019 Apr 29;133(8):997-1010. doi: 10.1042/CS20190111. Print 2019 Apr 30. Clin Sci (Lond). 2019. PMID: 30952809
80 results