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Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats.
Wong VKW, Qiu C, Xu SW, Law BYK, Zeng W, Wang H, Michelangeli F, Dias IRSR, Qu YQ, Chan TW, Han Y, Zhang N, Mok SWF, Chen X, Yu L, Pan H, Hamdoun S, Efferth T, Yu WJ, Zhang W, Li Z, Xie Y, Luo R, Jiang Q, Liu L. Wong VKW, et al. Among authors: yu l, yu wj. Br J Pharmacol. 2019 Aug;176(16):2922-2944. doi: 10.1111/bph.14718. Epub 2019 Jul 4. Br J Pharmacol. 2019. PMID: 31124139 Free PMC article.
Lychee seed polyphenol protects the blood-brain barrier through inhibiting Aβ(25-35)-induced NLRP3 inflammasome activation via the AMPK/mTOR/ULK1-mediated autophagy in bEnd.3 cells and APP/PS1 mice.
Xiong R, Zhou XG, Tang Y, Wu JM, Sun YS, Teng JF, Pan R, Law BY, Zhao Y, Qiu WQ, Wang XL, Liu S, Wang YL, Yu L, Yu CL, Mei QB, Qin DL, Wu AG. Xiong R, et al. Among authors: yu l, yu cl. Phytother Res. 2021 Feb;35(2):954-973. doi: 10.1002/ptr.6849. Epub 2020 Sep 6. Phytother Res. 2021. PMID: 32893437
Whole transcriptome sequencing and integrated network analysis elucidates the effects of 3,8-Di-O-methylellagic acid 2-O-glucoside derived from Sanguisorba offcinalis L., a novel differentiation inducer on erythroleukemia cells.
Long W, Liu S, Li XX, Shen X, Zeng J, Luo JS, Li KR, Wu AG, Yu L, Qin DL, Hu GQ, Yang J, Wu JM. Long W, et al. Among authors: yu l. Pharmacol Res. 2021 Apr;166:105491. doi: 10.1016/j.phrs.2021.105491. Epub 2021 Feb 12. Pharmacol Res. 2021. PMID: 33582247
Saponins isolated from Radix polygalae extent lifespan by modulating complement C3 and gut microbiota.
Zeng W, Wu AG, Zhou XG, Khan I, Zhang RL, Lo HH, Qu LQ, Song LL, Yun XY, Wang HM, Chen J, Ng JPL, Ren F, Yuan SY, Yu L, Tang Y, Huang GX, Wong VKW, Chung SK, Mok SWF, Qin DL, Sun HL, Liu L, Hsiao WLW, Law BYK. Zeng W, et al. Among authors: yu l. Pharmacol Res. 2021 Aug;170:105697. doi: 10.1016/j.phrs.2021.105697. Epub 2021 May 29. Pharmacol Res. 2021. PMID: 34062240
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