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HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice.
Samardzija M, Corna A, Gomez-Sintes R, Jarboui MA, Armento A, Roger JE, Petridou E, Haq W, Paquet-Durand F, Zrenner E, de la Villa P, Zeck G, Grimm C, Boya P, Ueffing M, Trifunović D. Samardzija M, et al. Among authors: gomez sintes r. Cell Death Differ. 2021 Apr;28(4):1317-1332. doi: 10.1038/s41418-020-00653-3. Epub 2020 Nov 6. Cell Death Differ. 2021. PMID: 33159184 Free PMC article.
Lysosomal cell death mechanisms in aging.
Gómez-Sintes R, Ledesma MD, Boya P. Gómez-Sintes R, et al. Ageing Res Rev. 2016 Dec;32:150-168. doi: 10.1016/j.arr.2016.02.009. Epub 2016 Mar 3. Ageing Res Rev. 2016. PMID: 26947122 Review.
Autophagy in the eye: Development, degeneration, and aging.
Boya P, Esteban-Martínez L, Serrano-Puebla A, Gómez-Sintes R, Villarejo-Zori B. Boya P, et al. Prog Retin Eye Res. 2016 Nov;55:206-245. doi: 10.1016/j.preteyeres.2016.08.001. Epub 2016 Aug 23. Prog Retin Eye Res. 2016. PMID: 27566190 Review.
Lysosomal membrane permeabilization and cell death.
Wang F, Gómez-Sintes R, Boya P. Wang F, et al. Among authors: gomez sintes r. Traffic. 2018 Dec;19(12):918-931. doi: 10.1111/tra.12613. Epub 2018 Sep 12. Traffic. 2018. PMID: 30125440 Free article. Review.
Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration.
Gomez-Sintes R, Xin Q, Jimenez-Loygorri JI, McCabe M, Diaz A, Garner TP, Cotto-Rios XM, Wu Y, Dong S, Reynolds CA, Patel B, de la Villa P, Macian F, Boya P, Gavathiotis E, Cuervo AM. Gomez-Sintes R, et al. Nat Commun. 2022 Jul 21;13(1):4220. doi: 10.1038/s41467-022-31869-1. Nat Commun. 2022. PMID: 35864098 Free PMC article.
Ambra1 haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration.
Ramírez-Pardo I, Villarejo-Zori B, Jiménez-Loygorri JI, Sierra-Filardi E, Alonso-Gil S, Mariño G, de la Villa P, Fitze PS, Fuentes JM, García-Escudero R, Ferrington DA, Gomez-Sintes R, Boya P. Ramírez-Pardo I, et al. Among authors: gomez sintes r. Autophagy. 2023 Mar;19(3):784-804. doi: 10.1080/15548627.2022.2103307. Epub 2022 Jul 24. Autophagy. 2023. PMID: 35875981 Free PMC article.
Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens.
Jiménez-Loygorri JI, Benítez-Fernández R, Viedma-Poyatos Á, Zapata-Muñoz J, Villarejo-Zori B, Gómez-Sintes R, Boya P. Jiménez-Loygorri JI, et al. Among authors: gomez sintes r. Prog Retin Eye Res. 2023 Sep;96:101205. doi: 10.1016/j.preteyeres.2023.101205. Epub 2023 Jul 15. Prog Retin Eye Res. 2023. PMID: 37454969 Free article. Review.
Standard Assays for the Study of Autophagy in the Ex Vivo Retina.
Gómez-Sintes R, Villarejo-Zori B, Serrano-Puebla A, Esteban-Martínez L, Sierra-Filardi E, Ramírez-Pardo I, Rodríguez-Muela N, Boya P. Gómez-Sintes R, et al. Cells. 2017 Oct 22;6(4):37. doi: 10.3390/cells6040037. Cells. 2017. PMID: 29065501 Free PMC article. Review.
Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus.
Engel T, Gómez-Sintes R, Alves M, Jimenez-Mateos EM, Fernández-Nogales M, Sanz-Rodriguez A, Morgan J, Beamer E, Rodríguez-Matellán A, Dunleavy M, Sano T, Avila J, Medina M, Hernandez F, Lucas JJ, Henshall DC. Engel T, et al. Among authors: gomez sintes r. Cell Death Dis. 2018 Sep 20;9(10):969. doi: 10.1038/s41419-018-0963-5. Cell Death Dis. 2018. PMID: 30237424 Free PMC article.
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