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Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma.
Kowalczyk JT, Wan X, Hernandez ER, Luo R, Lyons GC, Wilson KM, Gallardo DC, Isanogle KA, Robinson CM, Mendoza A, Heske CM, Chen JQ, Luo X, Kelly AE, Difilippantinio S, Robey RW, Thomas CJ, Sackett DL, Morrison DK, Randazzo PA, Jenkins LMM, Yohe ME. Kowalczyk JT, et al. Among authors: sackett dl. Mol Cancer Ther. 2021 Feb;20(2):307-319. doi: 10.1158/1535-7163.MCT-20-0525. Epub 2020 Nov 6. Mol Cancer Ther. 2021. PMID: 33158997 Free PMC article.
Proteasome inhibitors increase tubulin polymerization and stabilization in tissue culture cells: a possible mechanism contributing to peripheral neuropathy and cellular toxicity following proteasome inhibition.
Poruchynsky MS, Sackett DL, Robey RW, Ward Y, Annunziata C, Fojo T. Poruchynsky MS, et al. Among authors: sackett dl. Cell Cycle. 2008 Apr 1;7(7):940-9. doi: 10.4161/cc.7.7.5625. Epub 2008 Jan 17. Cell Cycle. 2008. PMID: 18414063 Free PMC article.
Microtubule-targeting agents augment the toxicity of DNA-damaging agents by disrupting intracellular trafficking of DNA repair proteins.
Poruchynsky MS, Komlodi-Pasztor E, Trostel S, Wilkerson J, Regairaz M, Pommier Y, Zhang X, Kumar Maity T, Robey R, Burotto M, Sackett D, Guha U, Fojo AT. Poruchynsky MS, et al. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1571-6. doi: 10.1073/pnas.1416418112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605897 Free PMC article.
443 results