Randazzo PA - Search Results

1

Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma.

Kowalczyk JT, Wan X, Hernandez ER, Luo R, Lyons GC, Wilson KM, Gallardo DC, Isanogle KA, Robinson CM, Mendoza A, Heske CM, Chen JQ, Luo X, Kelly AE, Difilippantinio S, Robey RW, Thomas CJ, Sackett DL, Morrison DK, Randazzo PA, Jenkins LMM, Yohe ME. Kowalczyk JT, et al. Among authors: randazzo pa. Mol Cancer Ther. 2021 Feb;20(2):307-319. doi: 10.1158/1535-7163.MCT-20-0525. Epub 2020 Nov 6. Mol Cancer Ther. 2021. PMID: 33158997 Free PMC article.

2

Mutational analysis of the Arf1*GTP/Arf GAP interface reveals an Arf1 mutant that selectively affects the Arf GAP ASAP1.

Luo R, Jacques K, Ahvazi B, Stauffer S, Premont RT, Randazzo PA. Luo R, et al. Among authors: randazzo pa. Curr Biol. 2005 Dec 6;15(23):2164-9. doi: 10.1016/j.cub.2005.10.065. Curr Biol. 2005. PMID: 16332543 Free article.

3

Kinetic analysis of Arf GAP1 indicates a regulatory role for coatomer.

Luo R, Randazzo PA. Luo R, et al. Among authors: randazzo pa. J Biol Chem. 2008 Aug 8;283(32):21965-77. doi: 10.1074/jbc.M802268200. Epub 2008 Jun 9. J Biol Chem. 2008. PMID: 18541532 Free PMC article.

4

Contribution of AZAP-Type Arf GAPs to cancer cell migration and invasion.

Ha VL, Luo R, Nie Z, Randazzo PA. Ha VL, et al. Among authors: randazzo pa. Adv Cancer Res. 2008;101:1-28. doi: 10.1016/S0065-230X(08)00401-6. Adv Cancer Res. 2008. PMID: 19055940 Free PMC article. Review.

5

Arf GAP2 is positively regulated by coatomer and cargo.

Luo R, Ha VL, Hayashi R, Randazzo PA. Luo R, et al. Among authors: randazzo pa. Cell Signal. 2009 Jul;21(7):1169-79. doi: 10.1016/j.cellsig.2009.03.006. Epub 2009 Mar 16. Cell Signal. 2009. PMID: 19296914 Free PMC article.

6

ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking.

Yoon HY, Kales SC, Luo R, Lipkowitz S, Randazzo PA. Yoon HY, et al. Among authors: randazzo pa. Biol Cell. 2011 Apr;103(4):171-84. doi: 10.1042/BC20100154. Biol Cell. 2011. PMID: 21275903 Free PMC article.

7

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

Luo R, Akpan IO, Hayashi R, Sramko M, Barr V, Shiba Y, Randazzo PA. Luo R, et al. Among authors: randazzo pa. J Biol Chem. 2012 May 18;287(21):17176-17185. doi: 10.1074/jbc.M111.334458. Epub 2012 Mar 27. J Biol Chem. 2012. PMID: 22453919 Free PMC article.

8

Approaches to studying Arf GAPs in cells: in vitro assay with isolated focal adhesions.

Chen PW, Jian X, Luo R, Randazzo PA. Chen PW, et al. Among authors: randazzo pa. Curr Protoc Cell Biol. 2012 Jun;Chapter 17:17.13.1-17.13.20. doi: 10.1002/0471143030.cb1713s55. Curr Protoc Cell Biol. 2012. PMID: 23129116 Free PMC article. Review.

9

The Arf6 GTPase-activating proteins ARAP2 and ACAP1 define distinct endosomal compartments that regulate integrin α5β1 traffic.

Chen PW, Luo R, Jian X, Randazzo PA. Chen PW, et al. Among authors: randazzo pa. J Biol Chem. 2014 Oct 31;289(44):30237-30248. doi: 10.1074/jbc.M114.596155. Epub 2014 Sep 15. J Biol Chem. 2014. PMID: 25225293 Free PMC article.

10

Simple in vitro assay of Arf GAPs and preparation of Arf proteins as substrates.

Chen PW, Jian X, Luo R, Randazzo PA. Chen PW, et al. Among authors: randazzo pa. Methods Cell Biol. 2015;130:69-80. doi: 10.1016/bs.mcb.2015.03.021. Epub 2015 Jun 11. Methods Cell Biol. 2015. PMID: 26360029 Free PMC article.

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