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The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin.
Yang J, Yan W, Yu Y, Wang Y, Yang T, Xue L, Yuan X, Long C, Liu Z, Chen X, Hu M, Zheng L, Qiu Q, Pei H, Li D, Wang F, Bai P, Wen J, Ye H, Chen L. Yang J, et al. Among authors: qiu q. J Biol Chem. 2018 Jun 15;293(24):9461-9472. doi: 10.1074/jbc.RA117.001658. Epub 2018 Apr 24. J Biol Chem. 2018. PMID: 29691282 Free PMC article.
Purinostat Mesylate Is a Uniquely Potent and Selective Inhibitor of HDACs for the Treatment of BCR-ABL-Induced B-Cell Acute Lymphoblastic Leukemia.
Yang L, Qiu Q, Tang M, Wang F, Yi Y, Yi D, Yang Z, Zhu Z, Zheng S, Yang J, Pei H, Zheng L, Chen Y, Gou L, Luo L, Deng X, Ye H, Hu Y, Niu T, Chen L. Yang L, et al. Among authors: qiu q. Clin Cancer Res. 2019 Dec 15;25(24):7527-7539. doi: 10.1158/1078-0432.CCR-19-0516. Epub 2019 Aug 22. Clin Cancer Res. 2019. PMID: 31439580
Correction: Non-toxic dose of liposomal honokiol suppresses metastasis of hepatocellular carcinoma through destabilizing EGFR and inhibiting the downstream pathways.
Yang J, Pei H, Luo H, Fu A, Yang H, Hu J, Zhao C, Chai L, Chen X, Shao X, Wang C, Wu W, Wan L, Ye H, Qiu Q, Peng A, Wei Y, Yang L, Chen L. Yang J, et al. Among authors: qiu q. Oncotarget. 2020 Sep 1;11(35):3350-3351. doi: 10.18632/oncotarget.27369. eCollection 2020 Sep 1. Oncotarget. 2020. PMID: 32934777 Free PMC article.
1,905 results