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Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Sobala ŁF, Fernandes PZ, Hakki Z, Thompson AJ, Howe JD, Hill M, Zitzmann N, Davies S, Stamataki Z, Butters TD, Alonzi DS, Williams SJ, Davies GJ. Sobala ŁF, et al. Among authors: alonzi ds. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29595-29601. doi: 10.1073/pnas.2013620117. Epub 2020 Nov 5. Proc Natl Acad Sci U S A. 2020. PMID: 33154157 Free PMC article.
Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo.
Chang J, Schul W, Butters TD, Yip A, Liu B, Goh A, Lakshminarayana SB, Alonzi D, Reinkensmeier G, Pan X, Qu X, Weidner JM, Wang L, Yu W, Borune N, Kinch MA, Rayahin JE, Moriarty R, Xu X, Shi PY, Guo JT, Block TM. Chang J, et al. Antiviral Res. 2011 Jan;89(1):26-34. doi: 10.1016/j.antiviral.2010.11.002. Epub 2010 Nov 10. Antiviral Res. 2011. PMID: 21073903 Free PMC article.
4-C-Me-DAB and 4-C-Me-LAB - enantiomeric alkyl-branched pyrrolidine iminosugars - are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group.
da Cruz FP, Newberry S, Jenkinson SF, Wormald MR, Butters TD, Alonzi DS, Nakagawa S, Becq F, Norez C, Nash RJ, Kato A, Fleet GW. da Cruz FP, et al. Among authors: alonzi ds. Tetrahedron Lett. 2011 Jan 12;52(2):219-223. doi: 10.1016/j.tetlet.2010.10.173. Tetrahedron Lett. 2011. PMID: 21157573 Free PMC article.
Urinary glycan markers for disease.
Alonzi DS, Su YH, Butters TD. Alonzi DS, et al. Biochem Soc Trans. 2011 Jan;39(1):393-8. doi: 10.1042/BST0390393. Biochem Soc Trans. 2011. PMID: 21265811 Review.
46 results