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Single-molecule DNA sequencing of widely varying GC-content using nucleotide release, capture and detection in microdroplets.
Puchtler TJ, Johnson K, Palmer RN, Talbot EL, Ibbotson LA, Powalowska PK, Knox R, Shibahara A, M S Cunha P, Newell OJ, Wu M, Chana J, Athanasopoulou EN, Waeber AM, Stolarek M, Silva AL, Mordaka JM, Haggis-Powell M, Xyrafaki C, Bush J, Topkaya IS, Sosna M, Ingham RJ, Huckvale T, Negrea A, Breiner B, Šlikas J, Kelly DJ, Dunning AJ, Bell NM, Dethlefsen M, Love DM, Dear PH, Kuleshova J, Podd GJ, Isaac TH, Balmforth BW, Frayling CA. Puchtler TJ, et al. Among authors: powalowska pk. Nucleic Acids Res. 2020 Dec 16;48(22):e132. doi: 10.1093/nar/gkaa987. Nucleic Acids Res. 2020. PMID: 33152076 Free PMC article.
Single-copy detection of somatic variants from solid and liquid biopsy.
Silva AL, Powalowska PK, Stolarek M, Gray ER, Palmer RN, Herman B, Frayling CA, Balmforth BW. Silva AL, et al. Among authors: powalowska pk. Sci Rep. 2021 Mar 16;11(1):6068. doi: 10.1038/s41598-021-85545-3. Sci Rep. 2021. PMID: 33727644 Free PMC article.
Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE.
Gray ER, Mordaka JM, Christoforou ER, von Bargen K, Potts ND, Xyrafaki C, Silva AL, Stolarek-Januszkiewicz M, Anton K, Powalowska PK, Andreazza S, Tomassini A, Palmer RN, Cooke A, Osborne RJ, Balmforth BW. Gray ER, et al. Among authors: powalowska pk. BMC Med Genomics. 2022 Oct 12;15(1):215. doi: 10.1186/s12920-022-01363-0. BMC Med Genomics. 2022. PMID: 36224552 Free PMC article.