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Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models.
Gunasekaran P, Yim MS, Ahn M, Soung NK, Park JE, Kim J, Bang G, Shin SC, Choi J, Kim M, Kim HN, Lee YH, Chung YH, Lee K, EunKyeong Kim E, Jeon YH, Kim MJ, Lee KR, Kim BY, Lee KS, Ryu EK, Bang JK. Gunasekaran P, et al. Among authors: soung nk. J Med Chem. 2020 Dec 10;63(23):14905-14920. doi: 10.1021/acs.jmedchem.0c01451. Epub 2020 Nov 3. J Med Chem. 2020. PMID: 33142063 Free PMC article.
Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.
Lee KH, Hwang JA, Kim SO, Kim JH, Shin SC, Kim EE, Lee KS, Rhee K, Jeon BH, Bang JK, Cha-Molstad H, Soung NK, Jang JH, Ko SK, Lee HG, Ahn JS, Kwon YT, Kim BY. Lee KH, et al. Among authors: soung nk. J Biol Chem. 2018 Jan 19;293(3):847-862. doi: 10.1074/jbc.M117.802587. Epub 2017 Nov 30. J Biol Chem. 2018. PMID: 29191835 Free PMC article.
Antibacterial AZT derivative regulates metastasis of breast cancer cells.
Chirumarry S, Soung NK, Han J, Kim EY, Ryu EK, Lee YH, Shin SY, Gunasekaran P, Bang JK. Chirumarry S, et al. Among authors: soung nk. Eur J Med Chem. 2020 May 1;193:112233. doi: 10.1016/j.ejmech.2020.112233. Epub 2020 Mar 19. Eur J Med Chem. 2020. PMID: 32199136
Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
Yun SM, Moulaei T, Lim D, Bang JK, Park JE, Shenoy SR, Liu F, Kang YH, Liao C, Soung NK, Lee S, Yoon DY, Lim Y, Lee DH, Otaka A, Appella E, McMahon JB, Nicklaus MC, Burke TR Jr, Yaffe MB, Wlodawer A, Lee KS. Yun SM, et al. Among authors: soung nk. Nat Struct Mol Biol. 2009 Aug;16(8):876-82. doi: 10.1038/nsmb.1628. Epub 2009 Jul 13. Nat Struct Mol Biol. 2009. PMID: 19597481 Free PMC article.
Polo-box domain: a versatile mediator of polo-like kinase function.
Park JE, Soung NK, Johmura Y, Kang YH, Liao C, Lee KH, Park CH, Nicklaus MC, Lee KS. Park JE, et al. Among authors: soung nk. Cell Mol Life Sci. 2010 Jun;67(12):1957-70. doi: 10.1007/s00018-010-0279-9. Epub 2010 Feb 11. Cell Mol Life Sci. 2010. PMID: 20148280 Free PMC article. Review.
66 results