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Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models.
Gunasekaran P, Yim MS, Ahn M, Soung NK, Park JE, Kim J, Bang G, Shin SC, Choi J, Kim M, Kim HN, Lee YH, Chung YH, Lee K, EunKyeong Kim E, Jeon YH, Kim MJ, Lee KR, Kim BY, Lee KS, Ryu EK, Bang JK. Gunasekaran P, et al. Among authors: shin sc. J Med Chem. 2020 Dec 10;63(23):14905-14920. doi: 10.1021/acs.jmedchem.0c01451. Epub 2020 Nov 3. J Med Chem. 2020. PMID: 33142063 Free PMC article.
Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.
Lee KH, Hwang JA, Kim SO, Kim JH, Shin SC, Kim EE, Lee KS, Rhee K, Jeon BH, Bang JK, Cha-Molstad H, Soung NK, Jang JH, Ko SK, Lee HG, Ahn JS, Kwon YT, Kim BY. Lee KH, et al. Among authors: shin sc. J Biol Chem. 2018 Jan 19;293(3):847-862. doi: 10.1074/jbc.M117.802587. Epub 2017 Nov 30. J Biol Chem. 2018. PMID: 29191835 Free PMC article.
Small molecule activator of Nm23/NDPK as an inhibitor of metastasis.
Lee JJ, Kim HS, Lee JS, Park J, Shin SC, Song S, Lee E, Choi JE, Suh JW, Lee H, Kim EE, Seo EK, Shin DH, Lee HY, Lee HY, Lee KJ. Lee JJ, et al. Among authors: shin dh, shin sc. Sci Rep. 2018 Jul 19;8(1):10909. doi: 10.1038/s41598-018-29101-6. Sci Rep. 2018. PMID: 30026594 Free PMC article.
Structure of ubiquitin-fold modifier 1-specific protease UfSP2.
Ha BH, Jeon YJ, Shin SC, Tatsumi K, Komatsu M, Tanaka K, Watson CM, Wallis G, Chung CH, Kim EE. Ha BH, et al. Among authors: shin sc. J Biol Chem. 2011 Mar 25;286(12):10248-57. doi: 10.1074/jbc.M110.172171. Epub 2011 Jan 12. J Biol Chem. 2011. PMID: 21228277 Free PMC article.
466 results