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Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models.
Gunasekaran P, Yim MS, Ahn M, Soung NK, Park JE, Kim J, Bang G, Shin SC, Choi J, Kim M, Kim HN, Lee YH, Chung YH, Lee K, EunKyeong Kim E, Jeon YH, Kim MJ, Lee KR, Kim BY, Lee KS, Ryu EK, Bang JK. Gunasekaran P, et al. Among authors: jeon yh. J Med Chem. 2020 Dec 10;63(23):14905-14920. doi: 10.1021/acs.jmedchem.0c01451. Epub 2020 Nov 3. J Med Chem. 2020. PMID: 33142063 Free PMC article.
Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Lim S, Cho HY, Kim DG, Roh Y, Son SY, Mushtaq AU, Kim M, Bhattarai D, Sivaraman A, Lee Y, Lee J, Yang WS, Kim HK, Kim MH, Lee K, Jeon YH, Kim S. Lim S, et al. Among authors: jeon yh. Nat Chem Biol. 2020 Jan;16(1):31-41. doi: 10.1038/s41589-019-0415-2. Epub 2019 Dec 2. Nat Chem Biol. 2020. PMID: 31792442
AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.
Kim DG, Choi Y, Lee Y, Lim S, Kong J, Song J, Roh Y, Harmalkar DS, Lee K, Goo JI, Cho HY, Mushtaq AU, Lee J, Park SH, Kim D, Min BS, Lee KY, Jeon YH, Lee S, Lee K, Kim S. Kim DG, et al. Among authors: jeon yh. Nat Commun. 2022 May 11;13(1):2572. doi: 10.1038/s41467-022-30149-2. Nat Commun. 2022. PMID: 35546148 Free PMC article.
Synthesis and biological evaluation of peptide-derived TSLP inhibitors.
Park S, Park Y, Son SH, Lee K, Jung YW, Lee KY, Jeon YH, Byun Y. Park S, et al. Among authors: jeon yh. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4710-4713. doi: 10.1016/j.bmcl.2017.09.010. Epub 2017 Sep 7. Bioorg Med Chem Lett. 2017. PMID: 28927768
549 results