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RNAi screen identifies essential regulators of human brain metastasis-initiating cells.
Singh M, Venugopal C, Tokar T, Brown KR, McFarlane N, Bakhshinyan D, Vijayakumar T, Manoranjan B, Mahendram S, Vora P, Qazi M, Dhillon M, Tong A, Durrer K, Murty N, Hallet R, Hassell JA, Kaplan DR, Cutz JC, Jurisica I, Moffat J, Singh SK. Singh M, et al. Among authors: brown kr. Acta Neuropathol. 2017 Dec;134(6):923-940. doi: 10.1007/s00401-017-1757-z. Epub 2017 Aug 1. Acta Neuropathol. 2017. PMID: 28766011
Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma.
Qazi MA, Vora P, Venugopal C, Adams J, Singh M, Hu A, Gorelik M, Subapanditha MK, Savage N, Yang J, Chokshi C, London M, Gont A, Bobrowski D, Grinshtein N, Brown KR, Murty NK, Nilvebrant J, Kaplan D, Moffat J, Sidhu S, Singh SK. Qazi MA, et al. Among authors: brown kr. Cancer Res. 2018 Sep 1;78(17):5023-5037. doi: 10.1158/0008-5472.CAN-18-0267. Epub 2018 Jun 26. Cancer Res. 2018. PMID: 29945963
Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells.
Vora P, Seyfrid M, Venugopal C, Qazi MA, Salim S, Isserlin R, Subapanditha M, O'Farrell E, Mahendram S, Singh M, Bakhshinyan D, Chokshi C, McFarlane N, Dvorkin-Gheva A, Brown KR, Murty N, Moffat J, Bader GD, Singh SK. Vora P, et al. Among authors: brown kr. J Neurooncol. 2019 Jul;143(3):417-428. doi: 10.1007/s11060-019-03192-1. Epub 2019 May 21. J Neurooncol. 2019. PMID: 31115870
Identification of five important genes to predict glioblastoma subtypes.
Tang Y, Qazi MA, Brown KR, Mikolajewicz N, Moffat J, Singh SK, McNicholas PD. Tang Y, et al. Among authors: brown kr. Neurooncol Adv. 2021 Oct 10;3(1):vdab144. doi: 10.1093/noajnl/vdab144. eCollection 2021 Jan-Dec. Neurooncol Adv. 2021. PMID: 34765972 Free PMC article.
CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment.
Seyfrid M, Maich WT, Shaikh VM, Tatari N, Upreti D, Piyasena D, Subapanditha M, Savage N, McKenna D, Mikolajewicz N, Han H, Chokshi C, Kuhlmann L, Khoo A, Salim SK, Archibong-Bassey B, Gwynne W, Brown K, Murtaza N, Bakhshinyan D, Vora P, Venugopal C, Moffat J, Kislinger T, Singh S. Seyfrid M, et al. J Immunother Cancer. 2022 Jan;10(1):e003289. doi: 10.1136/jitc-2021-003289. J Immunother Cancer. 2022. PMID: 35017149 Free PMC article.
Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma.
Qazi MA, Salim SK, Brown KR, Mikolajewicz N, Savage N, Han H, Subapanditha MK, Bakhshinyan D, Nixon A, Vora P, Desmond K, Chokshi C, Singh M, Khoo A, Macklin A, Khan S, Tatari N, Winegarden N, Richards L, Pugh T, Bock N, Mansouri A, Venugopal C, Kislinger T, Goyal S, Moffat J, Singh SK. Qazi MA, et al. Among authors: brown kr. Cell Rep. 2022 Sep 27;40(13):111420. doi: 10.1016/j.celrep.2022.111420. Cell Rep. 2022. PMID: 36170831 Free article.
Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma.
Gwynne WD, Suk Y, Custers S, Mikolajewicz N, Chan JK, Zador Z, Chafe SC, Zhai K, Escudero L, Zhang C, Zaslaver O, Chokshi C, Shaikh MV, Bakhshinyan D, Burns I, Chaudhry I, Nachmani O, Mobilio D, Maich WT, Mero P, Brown KR, Quaile AT, Venugopal C, Moffat J, Montenegro-Burke JR, Singh SK. Gwynne WD, et al. Among authors: brown kr. Cancer Cell. 2022 Dec 12;40(12):1488-1502.e7. doi: 10.1016/j.ccell.2022.10.009. Epub 2022 Nov 10. Cancer Cell. 2022. PMID: 36368321 Free article.
Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.
Kameda-Smith MM, Zhu H, Luo EC, Suk Y, Xella A, Yee B, Chokshi C, Xing S, Tan F, Fox RG, Adile AA, Bakhshinyan D, Brown K, Gwynne WD, Subapanditha M, Miletic P, Picard D, Burns I, Moffat J, Paruch K, Fleming A, Hope K, Provias JP, Remke M, Lu Y, Reya T, Venugopal C, Reimand J, Wechsler-Reya RJ, Yeo GW, Singh SK. Kameda-Smith MM, et al. Nat Commun. 2022 Dec 6;13(1):7506. doi: 10.1038/s41467-022-35118-3. Nat Commun. 2022. PMID: 36473869 Free PMC article.
296 results