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Design and Comprehensive Characterization of Tetramethylpyrazine (TMP) for Targeted Lung Delivery as Inhalation Aerosols in Pulmonary Hypertension (PH): In Vitro Human Lung Cell Culture and In Vivo Efficacy.
Muralidharan P, Acosta MF, Gomez AI, Grijalva C, Tang H, Yuan JX, Mansour HM. Muralidharan P, et al. Among authors: yuan jx. Antioxidants (Basel). 2021 Mar 11;10(3):427. doi: 10.3390/antiox10030427. Antioxidants (Basel). 2021. PMID: 33799587 Free PMC article.
Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.
Chen Y, Lu W, Yang K, Duan X, Li M, Chen X, Zhang J, Kuang M, Liu S, Wu X, Zou G, Liu C, Hong C, He W, Liao J, Hou C, Zhang Z, Zheng Q, Chen J, Zhang N, Tang H, Vanderpool RR, Desai AA, Rischard F, Black SM, Garcia JGN, Makino A, Yuan JX, Zhong N, Wang J. Chen Y, et al. Among authors: yuan jx. Br J Pharmacol. 2020 Jun;177(12):2743-2764. doi: 10.1111/bph.15000. Epub 2020 Apr 27. Br J Pharmacol. 2020. PMID: 31976548 Free PMC article.
Biomechanical Forces and Oxidative Stress: Implications for Pulmonary Vascular Disease.
Zemskov EA, Lu Q, Ornatowski W, Klinger CN, Desai AA, Maltepe E, Yuan JX, Wang T, Fineman JR, Black SM. Zemskov EA, et al. Among authors: yuan jx. Antioxid Redox Signal. 2019 Oct 20;31(12):819-842. doi: 10.1089/ars.2018.7720. Epub 2019 Mar 19. Antioxid Redox Signal. 2019. PMID: 30623676 Free PMC article. Review.
Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension.
Tang H, Wu K, Wang J, Vinjamuri S, Gu Y, Song S, Wang Z, Zhang Q, Balistrieri A, Ayon RJ, Rischard F, Vanderpool R, Chen J, Zhou G, Desai AA, Black SM, Garcia JGN, Yuan JX, Makino A. Tang H, et al. Among authors: yuan jx. JACC Basic Transl Sci. 2018 Dec 31;3(6):744-762. doi: 10.1016/j.jacbts.2018.08.009. eCollection 2018 Dec. JACC Basic Transl Sci. 2018. PMID: 30623134 Free PMC article.
Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics.
Lu Q, Zemskov EA, Sun X, Wang H, Yegambaram M, Wu X, Garcia-Flores A, Song S, Tang H, Kangath A, Cabanillas GZ, Yuan JX, Wang T, Fineman JR, Black SM. Lu Q, et al. Among authors: yuan jx. Redox Biol. 2021 Jan;38:101785. doi: 10.1016/j.redox.2020.101785. Epub 2020 Nov 12. Redox Biol. 2021. PMID: 33221570 Free PMC article.
358 results